SKAP2
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Official Full Name
src kinase associated phosphoprotein 2
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Overview
The protein encoded by this gene belongs to the src family kinases. This protein is similar to the src kinase associated phosphoprotein 1. It is an adaptor protein that is thought to play an essential role in the src signaling pathway in various cells. It inhibits PTK2B/RAFTK activity and regulates alpha-synuclein phosphorylation. -
Synonyms
SKAP2; src kinase associated phosphoprotein 2; SCAP2, src family associated phosphoprotein 2; src kinase-associated phosphoprotein 2; RA70; SAPS; SKAP HOM; SKAP55R; Fyn associated phosphoprotein SKAP55 homologue; PRAP; Pyk2/RAFTK associated protein; SKAP-HOM; Src associated adaptor protein; Src family associated phosphoprotein 2; src kinase associated phosphoprotein of 55 related protein; SKAP-55HOM; SKAP55 homolog; Pyk2/RAFTK-associated protein; src-associated adaptor protein; retinoic acid-induced protein 70; src family-associated phosphoprotein 2; Fyn-associated phosphoprotein SKAP55 homologue; src-associated adapter protein with PH and SH3 domains; src kinase-associated phosphoprotein 55-related protein; src kinase-associated phosphoprotein of 55-related protein; SCAP2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
SKAP2 involved in several pathways and played different roles in them. We selected most pathways SKAP2 participated on our site, such as Cell-Cell communication, Signal regulatory protein (SIRP) family interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with SKAP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cell-Cell communication | CLDN20;CDH13;FERMT2;CDH24;KIRREL;CDH3;CADM2A;KIRREL3;CDH10 |
| Signal regulatory protein (SIRP) family interactions | SIRPB1;SKAP2 |
SKAP2 has several biochemical functions, for example, SH3/SH2 adaptor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SKAP2 itself. We selected most functions SKAP2 had, and list some proteins which have the same functions with SKAP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH3/SH2 adaptor activity | GAB1;HSH2D;SH3BGRL;GRAP;CNTNAP1;SLA2;CD28;ARHGAP1;GRB2 |
| protein binding | MRC2;EXOC1;COX6B2;DRAP1;IL13;FNBP1;MYH10;TAE1;NOA1 |
SKAP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SKAP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SKAP2.
PTPN22; FASLG; DNAJB6; GRB2
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