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SLA2

  • Official Full Name

    Src-like-adaptor 2

  • Overview

    This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.
  • Synonyms

    SLA2; Src-like-adaptor 2; C20orf156; src-like-adapter 2; FLJ21992; SLAP 2; A930009E21Rik; AI430952; MARS; MGC49845; Modulator of antigen receptor signaling; RGD1562071; SLA 2; SLAP2; Src like adapter protein 2; Src like adaptor 2; OTTHUMP00000030867; OTTHUMP00000030868; Src-like adapter protein-2; src-like adapter protein 2; SLAP-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLA2-2692H Recombinant Human SLA2, GST-tagged E.coli GST 1-261aa
Human SLA2-2474H Recombinant human SLA2, His-tagged E.coli His
Human SLA2-1809HCL Recombinant Human SLA2 293 Cell Lysate HEK293 N/A
Human SLA2-1810HCL Recombinant Human SLA2 293 Cell Lysate HEK293 N/A
Mouse Sla2-5896M Recombinant Mouse Sla2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque SLA2-4216R Recombinant Rhesus monkey SLA2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SLA2-4032R Recombinant Rhesus Macaque SLA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SLA2-4032R-B Recombinant Rhesus Macaque SLA2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SLA2-6405Z Recombinant Zebrafish SLA2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SLA2 involved in several pathways and played different roles in them. We selected most pathways SLA2 participated on our site, such as B Cell Receptor Signaling Pathway, TCR signaling in naive CD4+ T cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
B Cell Receptor Signaling PathwayBANK1;INPPL1;PDK2B;LCP2A;NEDD9;ARPC5;DUSP6;CDK6;NFKBIE
TCR signaling in naive CD4+ T cellsDBNL;STK39;SLA2

SLA2 has several biochemical functions, for example, SH3/SH2 adaptor activity, protein N-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLA2 itself. We selected most functions SLA2 had, and list some proteins which have the same functions with SLA2. You can find most of the proteins on our site.

Function Related Protein
SH3/SH2 adaptor activitySOCS2;STAP1;ARHGAP4;TOB1;ITSN2;GRB14;SH2B2;STAM;LASP1
protein N-terminus bindingHESX1;PEX19;MORF4L1;PARP1;EIF5A;NCOA3;TGFB1;NCOA1;YWHAQ
protein bindingHIST1H1A;ACP1;SGK1;MOAP1;RPIA;PRPF8;TGS1;MED23;SUV39H1

SLA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLA2.

ERBB2; MET; KIT; GAB1; EGFR; ALB

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