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SLC16A8

Official Full Name

solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
Overview

SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across;cell membranes (Yoon et al., 1999 (PubMed 10493836)).
Synonyms

SLC16A8; solute carrier family 16, member 8 (monocarboxylic acid transporter 3); solute carrier 16 (monocarboxylic acid transporters), member 8; monocarboxylate transporter 3; MCT3; REMP; MCT 3; Monocarboxylic acid transporter 3; OTTHUMP00000028510; Solute carrier 16 (monocarboxylic acid transporters) member 8; Solute carrier family 16 member 8;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	SLC16A8-15238M	Recombinant Mouse SLC16A8 Protein	Mammalian Cell	His	Inquiry
Mouse	SLC16A8-8238M	Recombinant Mouse SLC16A8 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	SLC16A8-8238M-B	Recombinant Mouse SLC16A8 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	SLC16A8-11910Z	Recombinant Zebrafish SLC16A8	Mammalian Cell	His	Inquiry
Chicken	SLC16A8-6697C	Recombinant Chicken SLC16A8	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

SLC16A8 involved in several pathways and played different roles in them. We selected most pathways SLC16A8 participated on our site, such as Basigin interactions, Cell surface interactions at the vascular wall, Hemostasis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC16A8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Basigin interactions	SLC3A2A;PPIA;NADL1.1;SLC16A1;SLC3A2B;ITGB1B.1;BSG;SLC7A8A;SLC7A11
Cell surface interactions at the vascular wall	SLC3A2B;MERTK;GRB14;GRB7;SLC7A6;FN1B;BSG;ESAMA;SIRPA
Hemostasis	IRF1B;S100A10B;S100A10A;GATA2A;GRB14;ESAMA;F3A;MERTK;TREM1
Metabolism	ACOT6;ARL2;SULT1ST5;NAGS;CYP3A7-CYP3AP1;ALOX5B.3;ADH8B;NAMPT;ETFB
Proton-coupled monocarboxylate transport	SLC16A8;SLC16A1;SLC16A7
Pyruvate metabolism	ACYP2;GRHPRA;BRP44;ACACA;PDP2;ALDH7A1;ackA;PDK4;LDHB
Pyruvate metabolism and Citric Acid (TCA) cycle	PDK3B;BRP44;PDPR;SLC16A8;ADHFE1;PDK3;PDP1;PDK2B;D2HGDH
SLC-mediated transmembrane transport	SLC30A8;SLC24A6;SLC2A8;SLC26A2;SLC27A4;SLC6A19A;SLC38A3A;SLC1A3B;SLC22A6

SLC16A8 has several biochemical functions, for example, lactate transmembrane transporter activity, monocarboxylic acid transmembrane transporter activity, symporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC16A8 itself. We selected most functions SLC16A8 had, and list some proteins which have the same functions with SLC16A8. You can find most of the proteins on our site.

Function	Related Protein
lactate transmembrane transporter activity	SLC16A12B;SLC16A8;SLC16A1;SLC16A7;SLC16A12;SLC16A5;SLC16A3;SLC5A12
monocarboxylic acid transmembrane transporter activity	SLC16A9B;SLC16A8;PPP1R42;SLC16A4;SLC16A6A;SLC16A9;SLC16A6;SLC16A11;SLC16A3
symporter activity	SLC1A3B;SLC6A13;SLC1A8B;SLC17A6B;SLC16A13;SLC16A2;SLC10A5;SLC15A3;SLC16A8

SLC16A8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC16A8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC16A8.