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SLC17A7

Official Full Name

solute carrier family 17 (vesicular glutamate transporter), member 7
Overview

The protein encoded by this gene is a vesicle-bound, sodium-dependent phosphate transporter that is specifically expressed in the neuron-rich regions of the brain. It is preferentially associated with the membranes of synaptic vesicles and functions in glutamate transport. The protein shares 82% identity with the differentiation-associated Na-dependent inorganic phosphate cotransporter and they appear to form a distinct class within the Na+/Pi cotransporter family. [provided by RefSeq, Jul 2008]
Synonyms

SLC17A7; solute carrier family 17 (vesicular glutamate transporter), member 7; BNPI; VGLUT1; vesicular glutamate transporter 1; solute carrier family 17 member 7; brain-specific Na-dependent inorganic phosphate cotransporter; brain-specific Na(+)-dependent inorganic phosphate cotransporter; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Mouse
Rat

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	SLC17A7-15246M	Recombinant Mouse SLC17A7 Protein	Mammalian Cell	His	Inquiry
Mouse	SLC17A7-8244M-B	Recombinant Mouse SLC17A7 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	SLC17A7-8244M	Recombinant Mouse SLC17A7 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	SLC17A7-5442R	Recombinant Rat SLC17A7 Protein	Mammalian Cell	His	Inquiry
Rat	SLC17A7-5101R	Recombinant Rat SLC17A7 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	SLC17A7-5101R-B	Recombinant Rat SLC17A7 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SLC17A7 Related Articles

SLC17A7 involved in several pathways and played different roles in them. We selected most pathways SLC17A7 participated on our site, such as Synaptic vesicle cycle, Retrograde endocannabinoid signaling, Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC17A7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Synaptic vesicle cycle	ATP6V1D;STX2;SLC18A1;SNAP25;CPLX2;UNC13A;ATP6V0E1;ATP6V0B;ATP6V0D1
Retrograde endocannabinoid signaling	PRKCB;GABRR3;GNG12;GNG11;PLCB3;GABRG1;GABRG2;GABRB3;PRKACA
Glutamatergic synapse	GNB4;SLC17A8;GRIN2D;TRPC1;GNG3;GRM6;HOMER2;PLD2;GNG12
Nicotine addiction	GABRE;GABRA2;GRIN1;SLC17A7;GRIA1;GABRR1;GABRB1;GABRA4;GABRA6

SLC17A7 has several biochemical functions, for example, extracellular-glutamate-gated chloride channel activity, inorganic phosphate transmembrane transporter activity, sodium-dependent phosphate transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC17A7 itself. We selected most functions SLC17A7 had, and list some proteins which have the same functions with SLC17A7. You can find most of the proteins on our site.

Function	Related Protein
extracellular-glutamate-gated chloride channel activity
inorganic phosphate transmembrane transporter activity	SLC17A7;ANKH;SLC20A1B;SLC20A1A;SLC20A1;SLC20A2
sodium-dependent phosphate transmembrane transporter activity	SLC34A2;SLC17A1;SLC34A2B;SLC17A2;SLC34A2A;SLC17A7A;SLC34A3;SLC17A3;SLC17A4
sodium:inorganic phosphate symporter activity	SLC17A7A;SLC20A1;SLC20A1B;SLC17A7;SLC20A2;SLC20A1A
symporter activity	SLC5A4;SLC1A7A;SLC6A6B;SLC15A5;SLC17A1;SLC16A4;SLC46A2;SLC38A1;SLC34A3

SLC17A7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC17A7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC17A7.

Dlg4

Heyne, HO; Lautenschlager, S; et al. Genetic Influences on Brain Gene Expression in Rats Selected for Tameness and Aggression. GENETICS 198:1277-+(2014).

Kim, JH; Kim, JH; et al. Chronic Sleep Deprivation-Induced Proteome Changes in Astrocytes of the Rat Hypothalamus. JOURNAL OF PROTEOME RESEARCH 13:4047-4061(2014).