SLC22A8
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Official Full Name
solute carrier family 22 (organic anion transporter), member 8
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Overview
This gene encodes a protein involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. -
Synonyms
SLC22A8; solute carrier family 22 (organic anion transporter), member 8; solute carrier family 22 member 8; rOat3; organic anion transporter 3; solute carrier family 22 ,member 8; OCT3; Oat3; Roct; MGC93369;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- SLC22A8 Related Articles
SLC22A8 involved in several pathways and played different roles in them. We selected most pathways SLC22A8 participated on our site, such as Bile secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC22A8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Bile secretion | PRKACB;BAAT;ATP1B4;SULT2A1;SLC22A1;SLC22A8;ADCY3;ADCY7;SLC27A5 |
SLC22A8 has several biochemical functions, for example, inorganic anion exchanger activity, sodium-independent organic anion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC22A8 itself. We selected most functions SLC22A8 had, and list some proteins which have the same functions with SLC22A8. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| inorganic anion exchanger activity | SLC4A3;SLC22A24;Slc4a2;SLC22A20;SLC4A2B;SLC4A4;SLC4A1A;SLC22A8;SLC4A1 |
| sodium-independent organic anion transmembrane transporter activity | SLCO1F4;SLCO3A1;SLC22A7;SLCO2B1;SLC22A12;SLC22A24;SLC22A6;SLCO4A1;SLC22A9 |
SLC22A8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC22A8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC22A8.
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