SLC24A2
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Official Full Name
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
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Overview
This gene encodes a member of the calcium/cation antiporter superfamily of transport proteins. The encoded protein;belongs to the SLC24 branch of exchangers, which can mediate the extrusion of one Ca2+ ion and one K+ ion in exchange;for four Na+ ions. This family member is a retinal cone/brain exchanger that can mediate a light-induced decrease in;free Ca2+ concentration. This protein may also play a neuroprotective role during ischemic brain injury. Alternative;splicing results in multiple transcript variants. -
Synonyms
SLC24A2; solute carrier family 24 (sodium/potassium/calcium exchanger), member 2; sodium/potassium/calcium exchanger 2; Na(+)/K(+)/Ca(2+) exchange protein 2; NCKX 2; OTTHUMP00000045115; Retinal cone Na Ca+K exchanger; solute carrier family 24 (sodium/potassium/calcium exchanger) member 2; Solute carrier family 24 member 2; retinal cone Na-Ca+K exchanger; solute carrier family 24, member 2; Na(+)/K(+)/Ca(2+)-exchange protein 2; potassium-dependent sodium-calcium exchanger; Nckx2;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Rat | SLC24A2-5466R | Recombinant Rat SLC24A2 Protein | Mammalian Cell | His |
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| Rat | SLC24A2-5125R-B | Recombinant Rat SLC24A2 Protein Pre-coupled Magnetic Beads | HEK293 |
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| Rat | SLC24A2-5125R | Recombinant Rat SLC24A2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Zebrafish | SLC24A2-4363Z | Recombinant Zebrafish SLC24A2 | Mammalian Cell | His |
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| Chicken | SLC24A2-1163C | Recombinant Chicken SLC24A2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
SLC24A2 involved in several pathways and played different roles in them. We selected most pathways SLC24A2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC24A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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SLC24A2 has several biochemical functions, for example, calcium channel activity, calcium ion binding, calcium, potassium:sodium antiporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC24A2 itself. We selected most functions SLC24A2 had, and list some proteins which have the same functions with SLC24A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium channel activity | TRPC4A;GRIN2B;CACNG1A;TRPM6;TRPV2;SLC24A5;CHRNA10;CATSPER2;CCDC109A |
| calcium ion binding | PCDH2G2;RASGRP1;THBS3B;MICU1;CLSTN1;PCDHA6;EDIL3;MYLZ3;MYL6 |
| calcium, potassium:sodium antiporter activity | SLC24A5;SLC24A2;SLC24A1;SLC24A4A;SLC24A4 |
| potassium ion binding | SLC24A4A;SLC24A2;HDAC4;KCNA4;PKMA;ATP1A1;SLC24A1;PDXK;SLC24A5 |
| sodium ion binding | SLC34A2;ATP1A1;SLC24A4;SLC24A5;SCN9A;SLC24A2;SLC24A4A;SLC24A1;CAPN3 |
| symporter activity | SLC20A1B;SLC1A7B;SLC34A2;SLC5A11;SLC6A6;SLC6A19B;SLC38A1;SLC6A4A;SLC25A18 |
SLC24A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC24A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC24A2.
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