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SLC25A13

  • Official Full Name

    solute carrier family 25, member 13 (citrin)

  • Overview

    This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    SLC25A13; solute carrier family 25, member 13 (citrin); CTLN2; calcium-binding mitochondrial carrier protein Aralar2; ARALAR2; CITRIN; mitochondrial aspartate glutamate carrier 2; AI785475; Calcium binding mitochondrial carrier protein Aralar2; Ctrn; RGD1565889; Solute carrier family 25 (citrin) member 13; Solute carrier family 25 member 13 (citrin); Solute carrier family 25 member 13; OTTHUMP00000024692;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Mus musculus (Mouse)
  • E.coli
  • E.coli expression system
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • 8His
  • MBP,Flag
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC25A13-558H Recombinant Human SLC25A13 Protein, His-tagged E.coli His
Human SLC25A13-1622HCL Recombinant Human SLC25A13 cell lysate N/A
Human SLC25A13-0690H Recombinant Human SLC25A13 Protein (A2-P675), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag A2-P675
Cynomolgus Monkey SLC25A13-925C Recombinant Cynomolgus SLC25A13 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey SLC25A13-668C Recombinant Cynomolgus Monkey SLC25A13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey SLC25A13-668C-B Recombinant Cynomolgus Monkey SLC25A13 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL32267HF Recombinant Full Length Human Calcium-Binding Mitochondrial Carrier Protein Aralar2(Slc25A13) Protein, His-Tagged E.coli expression system His Full Length (1-675)
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL12528MF Recombinant Full Length Macaca Fascicularis Calcium-Binding Mitochondrial Carrier Protein Aralar2(Slc25A13) Protein, His-Tagged E.coli expression system His Full Length (1-674)
Mus musculus (Mouse) RFL23648MF Recombinant Full Length Mouse Calcium-Binding Mitochondrial Carrier Protein Aralar2(Slc25A13) Protein, His-Tagged E.coli expression system His Full Length (1-676)
Chicken SLC25A13-2160C Recombinant Chicken SLC25A13 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SLC25A13 involved in several pathways and played different roles in them. We selected most pathways SLC25A13 participated on our site, such as Gluconeogenesis, Glucose metabolism, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
GluconeogenesisSLC25A12;SLC25A1A;GPR19;SLC25A10;SLC25A11;SLC25A1;SLC25A13
Glucose metabolismEPM2A;SLC25A1;PYGMB;GYG2;SLC25A10;AGL;SLC25A12;NHLRC1;SLC25A13
MetabolismPDP2;SUMF2;ABHD3;KCNJ11;SULT1C2;ADHFE1;KCNS3;ACOT11A;BHMT2
Metabolism of carbohydratesSLC35B2;TREH;SLC26A1;NHLRC1;B3GNT1;GYG1A;HAS1;KHK;ST3GAL3A
Metabolism of proteinsB3GNT8;EXOSC8;KLK13;C8orf84;SENP5;CBX8;EIF5;NSMCE1;PCSK1
Mitochondrial protein importTIMM23;TOMM22;PAM16;COX17;SLC25A12;TOMM7;CHCHD4;TOMM6;TIMM13

SLC25A13 has several biochemical functions, for example, L-aspartate transmembrane transporter activity, L-glutamate transmembrane transporter activity, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A13 itself. We selected most functions SLC25A13 had, and list some proteins which have the same functions with SLC25A13. You can find most of the proteins on our site.

Function Related Protein
L-aspartate transmembrane transporter activitySLC25A12;SLC38A7;SLC13A3;SLC1A6;SLC25A13
L-glutamate transmembrane transporter activitySLC25A22;SLC17A6;SLC25A13;SLC1A3;SLC1A7;SLC17A6B;SLC38A7;SLC1A2;SLC25A12
calcium ion bindingSNED1;SPOCK2;EGFL8;RCV1;LRP2;GUCA1D;RCN3;PLA2G4B;NOTCH1A
transporter activitySLC2A9L1;RBP4L;SYPL2B;SLC15A3;LCN12;AP2S1;SLC12A3;SLC16A10;SLC4A11

SLC25A13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A13 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A13.

USP50; BABAM1; BRE; 15-deoxy-delta(12,14; NDUFA4; IKBKB; XRCC3; SCO1; MT-CO2; MT-CO3; MYC; ALB; Tuba3a; COX6C; ARAF; COX4I1; RNH1; COX7A2; COX6B1; ATF2

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