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SLC25A27

  • Official Full Name

    solute carrier family 25, member 27

  • Overview

    Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.
  • Synonyms

    SLC25A27; solute carrier family 25, member 27; mitochondrial uncoupling protein 4; FLJ33552; UCP4; UCP 4; uncoupling protein 4; RP11-446F17.2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC25A27-544H Recombinant Human SLC25A27 Protein, His-tagged E.coli His
Human SLC25A27-1773HCL Recombinant Human SLC25A27 293 Cell Lysate HEK293 N/A
Human SLC25A27-402H Recombinant Human SLC25A27 Protein, His-tagged E.coli N-His Ser21-Met317
Homo sapiens (Human) RFL34378HF Recombinant Full Length Human Mitochondrial Uncoupling Protein 4(Slc25A27) Protein, His-Tagged E.coli expression system His Full Length (1-323)
Rhesus Macaque SLC25A27-4250R Recombinant Rhesus monkey SLC25A27 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SLC25A27-4066R-B Recombinant Rhesus Macaque SLC25A27 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SLC25A27-4066R Recombinant Rhesus Macaque SLC25A27 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish SLC25A27-10665Z Recombinant Zebrafish SLC25A27 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SLC25A27 involved in several pathways and played different roles in them. We selected most pathways SLC25A27 participated on our site, such as Electron Transport Chain, Metabolism, Mitochondrial Uncoupling Proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A27 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Electron Transport ChainCOX4I1;ATPIF1;ATP5L;SLC25A27;UCP2;SURF1;COX11;COX7C;COX7A2
MetabolismSLC26A2;SULT2ST2;G0S2;CYP4T8;MARCKSB;COX6A1;CYP2K17;ADA;GCHFR
Mitochondrial Uncoupling ProteinsSLC25A14;SLC25A27;UCP3;UCP2
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.COX14;SURF1;NDUFAF4;C20orf7;ETFDH;TIMMDC1;UCP3;NDUFAF2;FAM36A
The citric acid (TCA) cycle and respiratory electron transportC20orf7;SLC25A14;ADHFE1;SURF1;NDUFAF7;SCO1;FAM36A;SLC25A27;C2orf56
The fatty acid cycling modelUCP3;SLC25A14;UCP2;SLC25A27
The proton buffering modelSLC25A14;SLC25A27

SLC25A27 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A27 itself. We selected most functions SLC25A27 had, and list some proteins which have the same functions with SLC25A27. You can find most of the proteins on our site.

Function Related Protein

SLC25A27 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A27 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A27.

PRKAR1A

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