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SLC25A5

  • Official Full Name

    solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5

  • Overview

    This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.
  • Synonyms

    SLC25A5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; ANT2; ADP/ATP translocase 2; 2F1; T2; T3; ANT 2; ADP/ATP carrier protein; ADP,ATP carrier protein 2; solute carrier family 25 member 5; ADP,ATP carrier p;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Rat
  • Rhesus Macaque
  • Tachyglossus aculeatus aculeatus (Southeast Australian short-beaked echidna)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • E.Coli or Yeast
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • 8His
  • MBP,Flag
  • Strep,Flag
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC25A5-2730H Recombinant Human SLC25A5, His-tagged E.coli His 1-298aa
Human SLC25A5-1757HCL Recombinant Human SLC25A5 293 Cell Lysate HEK293 N/A
Human SLC25A5-2026H-B Recombinant Human SLC25A5 Protein Pre-coupled Magnetic Beads HEK293
Human SLC25A5-300HFL Active Recombinant Full Length Human SLC25A5 Protein, C-Flag-tagged Mammalian cells Flag
Human SLC25A5-2026H Recombinant Human SLC25A5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SLC25A5-1550H Recombinant Human SLC25A5 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SLC25A5-0075H Recombinant Human SLC25A5 Protein (T2-T298), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag T2-T298
Human SLC25A5-0077H Recombinant Human SLC25A5 Protein (T2-Y297), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag T2-Y297
Human SLC25A5-0076H Recombinant Human SLC25A5 Protein (T2-T298), 8×His-Strep, Flag tagged Insect Cell 8His-Strep,Flag T2-T298
Mouse Slc25a5-3222M Recombinant Mouse Slc25a5, His-tagged E.Coli or Yeast His 298
Mouse SLC25A5-15336M Recombinant Mouse SLC25A5 Protein Mammalian Cell His
Mouse SLC25A5-8297M-B Recombinant Mouse SLC25A5 Protein Pre-coupled Magnetic Beads HEK293
Mouse SLC25A5-8297M Recombinant Mouse SLC25A5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Slc25a5-605M Recombinant Mouse Slc25a5 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat SLC25A5-5482R Recombinant Rat SLC25A5 Protein Mammalian Cell His
Rat SLC25A5-5141R Recombinant Rat SLC25A5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC25A5-5141R-B Recombinant Rat SLC25A5 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL17014BF Recombinant Full Length Bovine Adp/Atp Translocase 2(Slc25A5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Homo sapiens (Human) RFL22938HF Recombinant Full Length Human Adp/Atp Translocase 2(Slc25A5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Mus musculus (Mouse) RFL29648MF Recombinant Full Length Mouse Adp/Atp Translocase 2(Slc25A5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL31409PF Recombinant Full Length Pongo Abelii Adp/Atp Translocase 2(Slc25A5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Rhesus Macaque SLC25A5-4261R Recombinant Rhesus monkey SLC25A5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SLC25A5-4077R-B Recombinant Rhesus Macaque SLC25A5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SLC25A5-4077R Recombinant Rhesus Macaque SLC25A5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Tachyglossus aculeatus aculeatus (Southeast Australian short-beaked echidna) RFL18379TF Recombinant Full Length Tachyglossus Aculeatus Aculeatus Adp/Atp Translocase 2(Slc25A5) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (2-298)
Zebrafish SLC25A5-9521Z Recombinant Zebrafish SLC25A5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC25A5 Related Articles

SLC25A5 involved in several pathways and played different roles in them. We selected most pathways SLC25A5 participated on our site, such as Calcium signaling pathway, cGMP-PKG signaling pathway, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC25A5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayPLCD4;GRM5;PRKCB;ATP2B1A;AVPR1A;PHKG1;TACR1A;ADRB2;ERBB3B
cGMP-PKG signaling pathwayITPR1;MEF2D;SLC25A5;GNAQ;PIK3CG;NFATC4;SRF;INS2;SLC8A2
Parkinsons diseaseSDHD;PRKACB;Casp3;SLC25A5;NDUFA10;UQCRH;SLC18A2;mt-Atp8;VDAC3
Huntingtons diseaseATP5E;NDUFB5;ATP5O;APAF1;HTT;ATP5D;TBPL2;NDUFC2-KCTD14;COX5B
HTLV-I infectionHLA-DQA2;TRP53;DVL1;AKT1;HLA-DRB4;HLA-DOB;IL2RB;KRAS;MYB

SLC25A5 has several biochemical functions, for example, adenine transmembrane transporter activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC25A5 itself. We selected most functions SLC25A5 had, and list some proteins which have the same functions with SLC25A5. You can find most of the proteins on our site.

Function Related Protein
adenine transmembrane transporter activitySLC25A5;SLC25A4
poly(A) RNA bindingKIAA1324;TCOF1;CS;WIBG;ZMAT3;PPAN;SNRPC;TPR;MTPAP
protein bindingNRP1B;SMAGP;CA8;BIRC3;RGL2;RLTPR;ATXN1L;RBX1;RC3H2
ubiquitin protein ligase bindingZFP746;FAF2;MAP1LC3C;DAXX;ERBB2;NDUFS2;VCP;FLJ11011L;UBE2O

SLC25A5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC25A5 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC25A5.

LRRK2; P; ESR1; NCK2; TNFRSF1A; TNFRSF1B; NFKBIA; RELA; TRAF2; TRAF1; MAP3K1; RIPK1; TRADD; SMAD2; SLC35F6; MAP3K3

Di Noia, MA; Todisco, S; et al. The Human SLC25A33 and SLC25A36 Genes of Solute Carrier Family 25 Encode Two Mitochondrial Pyrimidine Nucleotide Transporters. JOURNAL OF BIOLOGICAL CHEMISTRY 289:33137-33148(2014).
Porcelli, V; Fiermonte, G; et al. The Human Gene SLC25A29, of Solute Carrier Family 25, Encodes a Mitochondrial Transporter of Basic Amino Acids. JOURNAL OF BIOLOGICAL CHEMISTRY 289:13374-13384(2014).
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