slc27a4
Share
  • Official Full Name
  • solute carrier family 27 (fatty acid transporter), member 4
  • Background
  • This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010]
  • Synonyms
  • SLC27A4; solute carrier family 27 (fatty acid transporter), member 4; IPS; FATP4; ACSVL4; long-chain fatty acid transport protein 4;
Cat.#:SLC27A4-2737HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLC27A4, GST-tagged
+Inquiry
Cat.#:SLC27A4-394HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human SLC27A4, His-tagged
+Inquiry
Cat.#:SLC27A4-929CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus SLC27A4 Protein, His-tagged
+Inquiry
Cat.#:SLC27A4-2488ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SLC27A4
+Inquiry
Cat.#:SLC27A4-001HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human SLC27A4 cell lysate
+Inquiry

Involved Pathway

SLC27A4 involved in several pathways and played different roles in them. We selected most pathways SLC27A4 participated on our site, such as Fat digestion and absorption, Insulin resistance, PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC27A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Fat digestion and absorption
PLA2G3; PLA2G2D; APOB; PPAP2A; FABP2; PLA2G12B; ACAT2; SCARB1; MOGAT3; MOGAT2
Insulin resistance
PRKCDA; IKBKB; SLC27A3; RPS6KA1; PPARGC1A; GSK3AA; PYGB; RPS6KA2; PRKAB1B; PPP1CBL
PPAR signaling pathway
Scd2; GK; ACSL1A; ADIPOQB; FABP4; FABP7B; PLTP; CYP8B1; SCP2A; ACAA1
SLC-mediated transmembrane transport
SLC28A1; SLC35A3B; SLC9A3.1; SLC12A1; SLC3A2A; SLC20A1A; PDZD11; SLC6A19B; SLC3A2B; SLC9A8
Transmembrane transport of small molecules
ANKHB; SLC22A18; SLC17A7A; ANO5B; TFA; TRPA1A; SLC39A14; SLC4A8; AQP11; SLC2A7
Transport of fatty acids
SLC27A4; LCN15; LCN9; APOD; LCN12; LCN1
Transport of vitamins, nucleosides, and related molecules
SLC5A6B; LCN12; SLC27A4; SLC35A3B; SLC35A3; SLC29A4; SLC28A1; SLC29A3; SLC35A3A; SLC29A1A

Protein Function

SLC27A4 has several biochemical functions, for example, fatty acid transporter activity, long-chain fatty acid-CoA ligase activity, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC27A4 itself. We selected most functions SLC27A4 had, and list some proteins which have the same functions with SLC27A4. You can find most of the proteins on our site.
Function
Related Protein
Function fatty acid transporter activity
Related Protein SLC27A1B; SLC27A2; SLC27A5; SLC27A1A; SLC27A4
Function long-chain fatty acid-CoA ligase activity
Related Protein SLC27A2; ACSL1; ACSL4; ACSL3; SLC27A1B; ACSBG1; SLC27A4; SLC27A5; SLC27A3; ACSL5
Function nucleotide binding
Related Protein RALAB; RBPMS; GRK7B; SFPQ; HNRNPH1; REV3L; CENPE; RBM15B; CPEB1B; HNRNPA1
Function very long-chain fatty acid-CoA ligase activity
Related Protein ACSL4; SLC27A4; SLC27A2; ACSBG1; SLC27A1B; SLC27A3; SLC27A1A; SLC27A5

Interacting Protein

SLC27A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC27A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC27A4.
BECN1; NIPAL4; TMBIM4; EPS8; Tpx2; E2F3; vpu; Sod1; PCNA; Dennd6a; Strn3