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SLC27A4

  • Official Full Name

    solute carrier family 27 (fatty acid transporter), member 4

  • Overview

    This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010]
  • Synonyms

    SLC27A4; solute carrier family 27 (fatty acid transporter), member 4; IPS; FATP4; ACSVL4; long-chain fatty acid transport protein 4;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Mus musculus (Mouse)
  • Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • 8His
  • MBP,Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC27A4-2737H Recombinant Human SLC27A4, GST-tagged E.coli GST 1-237aa
Human SLC27A4-394H Recombinant Human SLC27A4, His-tagged Human Cell His Gln483-Leu643
Human SLC27A4-001HCL Recombinant Human SLC27A4 cell lysate Human Cell N/A
Human SLC27A4-5580H Recombinant Human SLC27A4 Protein (Met1-Phe237), N-His tagged E.coli N-His Met1-Phe237
Human SLC27A4-0605H Recombinant Human SLC27A4 Protein (L2-L643), 8×His-MBP, Flag tagged Insect Cell 8His-MBP,Flag L2-L643
Cynomolgus Monkey SLC27A4-929C Recombinant Cynomolgus SLC27A4 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey SLC27A4-672C-B Recombinant Cynomolgus Monkey SLC27A4 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey SLC27A4-672C Recombinant Cynomolgus Monkey SLC27A4 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL482HF Recombinant Full Length Human Long-Chain Fatty Acid Transport Protein 4(Slc27A4) Protein, His-Tagged E.coli expression system His Full Length (1-643)
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL29445MF Recombinant Full Length Macaca Fascicularis Long-Chain Fatty Acid Transport Protein 4(Slc27A4) Protein, His-Tagged E.coli expression system His Full Length (1-643)
Mus musculus (Mouse) RFL11290MF Recombinant Full Length Mouse Long-Chain Fatty Acid Transport Protein 4(Slc27A4) Protein, His-Tagged E.coli expression system His Full Length (1-643)
Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) RFL36356PF Recombinant Full Length Pongo Abelii Long-Chain Fatty Acid Transport Protein 4(Slc27A4) Protein, His-Tagged E.coli expression system His Full Length (1-643)
Zebrafish SLC27A4-2488Z Recombinant Zebrafish SLC27A4 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLC27A4 Related Research Area

SLC27A4 involved in several pathways and played different roles in them. We selected most pathways SLC27A4 participated on our site, such as Fat digestion and absorption, Insulin resistance, PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC27A4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Fat digestion and absorptionPNLIPRP1;LIPF;PLA2G10;PPAP2C;PLA2G3;MOGAT3;SLC27A4;ABCG8;PLA2G5
Insulin resistancePRKCD;PPP1R3C;CREB3L3A;RPS6KA1;PIK3R5;INSRB;STAT3;PTPRFB;PRKAG1
PPAR signaling pathwayCD36;FABP1;LPL;RXRAA;ACSBG2;ACSL1;SLC27A1B;ACOX3;ACSL1B
SLC-mediated transmembrane transportSLC6A18;SLC9A6B;SLC1A2B;SLC39A2;SLC35D2;SLC39A14;LCN9;SLC6A11;SLC12A7
Transmembrane transport of small moleculesSLC1A7A;ADD3;HTR3C;SLC9A6A;TRPM1;CLIC2;FKBP1B;ATP7B;SLC1A7B
Transport of fatty acidsLCN12;LCN1;LCN15;SLC27A4;APOD;LCN9
Transport of vitamins, nucleosides, and related moleculesLCN12;SLC35A2;SLCO4C1;SLCO4A1;SLC27A4;SLC35B4;SLC5A6A;SLC29A1A;SLC28A2

SLC27A4 has several biochemical functions, for example, fatty acid transporter activity, long-chain fatty acid-CoA ligase activity, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC27A4 itself. We selected most functions SLC27A4 had, and list some proteins which have the same functions with SLC27A4. You can find most of the proteins on our site.

Function Related Protein
fatty acid transporter activitySLC27A1A;SLC27A4;SLC27A5;SLC27A1B;SLC27A2
long-chain fatty acid-CoA ligase activitySLC27A5;SLC27A4;SLC27A1B;ACSL4;ACSBG2;SLC27A2;ACSBG1;ACSL3;ACSL1
nucleotide bindingP2RX4A;PCXB;DAPK2A;HNRNPABA;SF3B6;ATP1A3A;VPS11;MAP3K12;PRKACAA
very long-chain fatty acid-CoA ligase activitySLC27A3;SLC27A1A;SLC27A4;ACSBG1;SLC27A2;SLC27A1B;ACSL4;SLC27A5

SLC27A4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC27A4 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC27A4.

BECN1; NIPAL4; TMBIM4; EPS8; Tpx2; E2F3; vpu; Sod1; PCNA; Dennd6a; Strn3

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