SLC35B2
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Official Full Name
solute carrier family 35, member B2
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Overview
Sulfotransferases (e.g., SULT4A1; MIM 608359) use an activated form of sulfate, 3-prime-phosphoadenosine;5-prime-phosphosulfate (PAPS), as a common sulfate donor for sulfation of glycoproteins, proteoglycans, and;glycolipids in the endoplasmic reticulum and Golgi apparatus. SLC35B2 is located in the microsomal membrane and;transports PAPS from the cytosol, where it is synthesized, into the Golgi lumen (Kamiyama et al., 2003 (PubMed;12716889)). -
Synonyms
SLC35B2; solute carrier family 35, member B2; adenosine 3-phospho 5-phosphosulfate transporter 1; UGTrel4; PAPS transporter 1; putative MAPK-activating protein PM15; putative NF-kappa-B-activating protein 48; solute carrier family 35 member B2 variant 2;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | SLC35B2-606HCL | Recombinant Human SLC35B2 lysate | HEK293 | N/A |
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| Mouse | Slc35b2-2696M | Recombinant Mouse Slc35b2 Protein, His&GST-tagged | E.coli | N-His&GST | Asp2-Tyr295 |
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| Dictyostelium discoideum (Slime mold) | RFL22028DF | Recombinant Full Length Dictyostelium Discoideum Adenosine 3'-Phospho 5'-Phosphosulfate Transporter 1(Slc35B2) Protein, His-Tagged | E.coli expression system | His | Full Length (1-359) |
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| Zebrafish | SLC35B2-11667Z | Recombinant Zebrafish SLC35B2 | Mammalian Cell | His |
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- Involved Pathway
- Protein Function
- Interacting Protein
- SLC35B2 Related Articles
SLC35B2 involved in several pathways and played different roles in them. We selected most pathways SLC35B2 participated on our site, such as Biological oxidations, Cytosolic sulfonation of small molecules, Glycosaminoglycan metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC35B2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Biological oxidations | CYP3A7-CYP3AP1;CYP2U1;AHCY;CYP2AD2;UGT1B3;CYP4F12;GSTO2;CYP2K16;CYP2A13 |
| Cytosolic sulfonation of small molecules | SULT1B1;SLC35B3;SULT2ST2;BPNT1;SULT1ST5;SULT1C2;Sult2a6;SLC35B2;SULT4A1 |
| Glycosaminoglycan metabolism | B3GNT2;UST;GPC5A;OGN;SLC35B2;HAS1;B3GNT3;KERA;B3GNT1 |
| Metabolism | ABCA1;G0S2;NUDT3B;NUDT5;CLPS;CKB;NFYAL;GDF1;CYP8B2 |
| Metabolism of carbohydrates | CHST14;B3GNT2A;B3GNT3;HPSE;GYG1A;UST;CHST9;SLC5A2;HAS3 |
| Phase II conjugation | UGT1B7;SULT1B1;UGT1B5;SLC26A2;UGT1B2;GGTLC1;UGT1B1;GLYAT;BPNT1 |
| SLC-mediated transmembrane transport | SLC15A4;SLC7A3;SLC1A3A;SLC28A1;SLC3A2B;SLC5A11;SLC2A6;SLC30A6;SLC6A20B |
| Transmembrane transport of small molecules | TRPM4C;AQP1A.2;RHCG2A;AZGP1;ABCG2D;TRPV3;ATP1A1A.4;NIPA1;SLC2A13 |
SLC35B2 has several biochemical functions, for example, 3-phosphoadenosine 5-phosphosulfate transmembrane transporter activity, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC35B2 itself. We selected most functions SLC35B2 had, and list some proteins which have the same functions with SLC35B2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 3-phosphoadenosine 5-phosphosulfate transmembrane transporter activity | |
| signal transducer activity | TAAR8C;PTK2AA;OLFCW1;TRHR2;VMN1R49;TAS2R134;SLC20A1;TAAR12A;OLFR150 |
SLC35B2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC35B2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC35B2.
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