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SLC39A8

  • Official Full Name

    solute carrier family 39 (zinc transporter), member 8

  • Overview

    This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
  • Synonyms

    SLC39A8; solute carrier family 39 (zinc transporter), member 8; solute carrier family 39 (metal ion transporter), member 8; zinc transporter ZIP8; BIGM103; ZIP-8; Zrt- and Irt-like protein 8; solute carrier family 39 member 8; LIV-1 subfamily of ZIP zinc;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLC39A8-671H Recombinant Human SLC39A8 Protein, GST-tagged Wheat Germ GST 1-460 aa
Human SLC39A8-1878H Recombinant Human SLC39A8 protein, GST-tagged E.coli GST 18-143 aa
Human SLC39A8-6817HF Recombinant Full Length Human SLC39A8 Protein, GST-tagged In Vitro Cell Free System GST 460 amino acids
Mouse SLC39A8-15441M Recombinant Mouse SLC39A8 Protein Mammalian Cell His
Mouse SLC39A8-8370M-B Recombinant Mouse SLC39A8 Protein Pre-coupled Magnetic Beads HEK293
Mouse SLC39A8-8370M Recombinant Mouse SLC39A8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC39A8-5535R Recombinant Rat SLC39A8 Protein Mammalian Cell His
Rat SLC39A8-5194R Recombinant Rat SLC39A8 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SLC39A8-5194R-B Recombinant Rat SLC39A8 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SLC39A8 involved in several pathways and played different roles in them. We selected most pathways SLC39A8 participated on our site, such as Metal ion SLC transporters, SLC-mediated transmembrane transport, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC39A8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metal ion SLC transportersSLC39A2;SLC30A1B;SLC30A3;SLC31A1;SLC39A1;SLC30A8;SLC30A5;SLC30A1A;SLC39A6
SLC-mediated transmembrane transportSLC1A4;SLC30A3;SLC30A2;SLC39A1;CTNS;SLC5A3A;SLC12A5B;APOD;SLC15A1B
Transmembrane transport of small moleculesTRPC4;CLCN5;MIPA;SLC35B4;ABCA7;SLC5A6A;CLCA1;SLC7A11;CP
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsSLC6A15;SLC22A15;SLC2A12;SLC2A15B;SLC10A6;SLC6A5;SLC22A7;SLC13A5A;SLC22A18
Zinc influx into cells by the SLC39 gene familySLC39A2;SLC39A8;SLC39A10;SLC39A3;SLC39A14;SLC39A5;SLC39A7;SLC39A6;SLC39A1
Zinc transportersSLC39A2;SLC39A7;SLC39A3;SLC30A1B;SLC39A5;SLC30A2;SLC39A6;SLC39A1;SLC30A3

SLC39A8 has several biochemical functions, for example, metal ion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC39A8 itself. We selected most functions SLC39A8 had, and list some proteins which have the same functions with SLC39A8. You can find most of the proteins on our site.

Function Related Protein
metal ion transmembrane transporter activitySLC39A14;SLC39A5;SLC39A8;SLC39A9;SLC39A6

SLC39A8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC39A8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC39A8.

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