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SLIRP

  • Official Full Name

    SRA stem-loop interacting RNA binding protein

  • Overview

    Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable;stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7;of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 (PubMed 16762838)).
  • Synonyms

    SLIRP; SRA stem-loop interacting RNA binding protein; C14orf156, chromosome 14 open reading frame 156; SRA stem-loop-interacting RNA-binding protein, mitochondrial; DC50; C14orf156; Chromosome 14 open reading frame 156; PD04872; SRA stem loop interacting RNA binding protein, mitochondrial;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SLIRP-974H Recombinant Human SLIRP Mammalian Cell His
Human SLIRP-8283HCL Recombinant Human C14orf156 293 Cell Lysate HEK293 N/A
Human SLIRP-4086H-B Recombinant Human SLIRP Protein Pre-coupled Magnetic Beads HEK293
Human SLIRP-4086H Recombinant Human SLIRP Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Slirp-5943M Recombinant Mouse Slirp Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SLIRP Related Articles

SLIRP involved in several pathways and played different roles in them. We selected most pathways SLIRP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SLIRP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

SLIRP has several biochemical functions, for example, nucleotide binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLIRP itself. We selected most functions SLIRP had, and list some proteins which have the same functions with SLIRP. You can find most of the proteins on our site.

Function Related Protein
nucleotide bindingGM4922;DNM1A;CPS1;CKBB;PKM;GNA13A;ACTA1A;CLCN4-2;DNM1B
poly(A) RNA bindingNLRP11;FAM98A;RDBP;TFB1M;TUFM;PPRC1;GPATCH4;MRPL40;RBM5
protein bindingRAB8A;USP20;ATP2A1;LAX1;SNX33;FAM151B;CUL1;GOLGA7;LGI4

SLIRP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLIRP here. Most of them are supplied by our site. Hope this information will be useful for your research of SLIRP.

CCDC102B; LRPPRC; MTUS2; KRT40; PNMA1; vpu; CSNK2A1

Colley, SM; Wintle, L; et al. Loss of the Nuclear Receptor Corepressor SLIRP Compromises Male Fertility. PLOS ONE 8:-(2013).
Hatchell, EC; Colley, SM; et al. SLIRP, a small SRA binding protein, is a nuclear receptor corepressor. MOLECULAR CELL 22:657-668(2006).
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