slpi
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  • Official Full Name
  • secretory leukocyte peptidase inhibitor
  • Background
  • This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity. [provided by RefSeq, Jul 2008]
  • Synonyms
  • SLPI; secretory leukocyte peptidase inhibitor; ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I; antileukoproteinase; HUSI-1; protease inhibitor WAP4; mucus proteinase inhibitor; seminal proteinase inhibitor; WAP four-disulfide core domain protein 4; secretory leukocyte protease inhibitor (antileukoproteinase);
Cat.#:SLPI-2550HTag:His
Source (Host):Insect CellsSpecies:Human
Product nameRecombinant Human SLPI protein, His-tagged
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Cat.#:SLPI-2551HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human SLPI, His tagged
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Cat.#:SLPI-2575HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Secretory Leukocyte Peptidase Inhibitor, His-tagged
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Cat.#:SLPI-30969THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLPI, His-tagged
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Cat.#:SLPI-15575MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Slpi protein, His-tagged
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Cat.#:Slpi-3516MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Slpi, His-tagged
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Cat.#:SLPI-4326RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SLPI Protein, His-tagged
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Cat.#:SLPI-001HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human SLPI cell lysate
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Cat.#:SLPI-530HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human SLPI cell lysate
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Protein Function

SLPI has several biochemical functions, for example, endopeptidase inhibitor activity, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SLPI itself. We selected most functions SLPI had, and list some proteins which have the same functions with SLPI. You can find most of the proteins on our site.
Function
Related Protein
Function endopeptidase inhibitor activity
Related Protein MUG1; SERPINF2; C3; ITIH2; SERPIND1; CST3; PROS1; AHSG; LPA; C3A.2
Function enzyme binding
Related Protein HOXA9; PPP3CB; NPC2; MSH2; PLCB1; PRKCH; JUND; USF1; HAND2; UBE2I
Function protein binding
Related Protein AKR1C1; LNPEP; EPB49; COL17A1; DDC; GNA13; WLS; RBP4; INTS9; HYPK
Function serine-type endopeptidase inhibitor activity
Related Protein CD109; PZP; APP; SPINT2; PI3; APPA; PAPLNB; Serpina1c; SERPINC1; PEBP1

Interacting Protein

SLPI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLPI here. Most of them are supplied by our site. Hope this information will be useful for your research of SLPI.
SGTA; FAM9B; ELANE; NFKBIB; MAPK8IP2

SLPI Related Articles

Hirbod, T; Kong, XR; et al. HIV Acquisition Is Associated with Increased Antimicrobial Peptides and Reduced HIV Neutralizing IgA in the Foreskin Prepuce of Uncircumcised Men. PLOS PATHOGENS 10:-(2014).
Woodham, AW; Da Silva, DM; et al. The S100A10 Subunit of the Annexin A2 Heterotetramer Facilitates L2-Mediated Human Papillomavirus Infection. PLOS ONE 7:-(2012).