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SMARCC1

  • Official Full Name

    SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

  • Overview

    The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008]
  • Synonyms

    SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1; Rsc8; SRG3; SWI3; BAF155; CRACC1; SWI/SNF complex subunit SMARCC1; BRG1-associated factor 155; SWI/SNF complex 155 kDa subunit; chromatin remodeling complex BAF155 subunit; mammalian chromatin remodeling complex BRG1-associated factor 155; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SMARCC1-1068H Recombinant Human SMARCC1 Protein (449-669 aa), His-SUMO-tagged E.coli His/SUMO 449-669 aa
Human SMARCC1-2348H Recombinant Human SMARCC1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SMARCC1-2741H Recombinant Human SMARCC1 Protein (449-669 aa), His-tagged Insect Cell His 449-669 aa
Human SMARCC1-1911H Recombinant Human SMARCC1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SMARCC1-4641H Recombinant Human SMARCC1 protein, His-SUMO-tagged E.coli His-SUMO 451-671aa
Mouse SMARCC1-15602M Recombinant Mouse SMARCC1 Protein Mammalian Cell His
Mouse SMARCC1-8465M Recombinant Mouse SMARCC1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Smarcc1-5961M Recombinant Mouse Smarcc1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SMARCC1-8465M-B Recombinant Mouse SMARCC1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SMARCC1 Related Research Area

SMARCC1 involved in several pathways and played different roles in them. We selected most pathways SMARCC1 participated on our site, such as Chromatin modifying enzymes, Chromatin organization, PluriNetWork, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMARCC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chromatin modifying enzymesHMG20B;ATXN7;MSL1A;ASH2L;ELP3;WDR77;SMARCB1B;RUVBL2;ANO9A
Chromatin organizationATXN7;ANO9A;JADE1;EED;MBIP;VPS72;SMARCD3B;PRDM16;PBRM1L
PluriNetWorkIPO7;RCOR2;ZFP57;KLF5;XPO4;ZSCAN10;SALL3;ZMYM2;SMARCC1
RMTs methylate histone argininesPRMT6;SMARCC2;PBRM1L;SMARCB1A;SMARCA2;SMARCA4;PBRM1;SMARCB1B;WDR77
TNF-alpha NF-kB Signaling PathwaySMARCA4A;SMARCB1A;TRPC4APA;TRAF4A;IKBKAP;ZFAND5A;CASP8AP2;SMARCC1;MTIF2

SMARCC1 has several biochemical functions, for example, DNA binding, contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA binding, contributes_to RNA polymerase II distal enhancer sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMARCC1 itself. We selected most functions SMARCC1 had, and list some proteins which have the same functions with SMARCC1. You can find most of the proteins on our site.

Function Related Protein
DNA bindingOTPB;RUNX1T1;PBX1A;ZIM2;E2F5;EHF;KLF14;H1M;PRDM12
contributes_to RNA polymerase II core promoter proximal region sequence-specific DNA bindingSMARCC2;ACTB;SMARCE1;RBBP4;HDAC1;MBD3;SMARCB1;MTA2;SMARCC1
contributes_to RNA polymerase II distal enhancer sequence-specific DNA bindingMBD3;SMARCE1;GATAD2B;SMARCA4;RBBP4;MTA2;ACTB;SMARCB1;ACTL6A
chromatin bindingYBX1;UBTFL;SOX14;PHF21A;WDHD1;ATOH1A;JARID2B;JARID2;FABP1
contributes_to nucleosomal DNA bindingSMARCC2;SMARCA4;SMARCB1;MTA2;RBBP4;ACTB;SMARCE1;HDAC1;CHD4
protein N-terminus bindingPEX19;GTF2H3;RPA2;KCNIP1;STX5;PHB2;ID1;SLC6A3;FEZ1
protein bindingCD247;HSPA8;GABARAP;AKAP12;TOP3A;ERO1L;SNX4;RBMY1B;GAGE1

SMARCC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMARCC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMARCC1.

Smarca4; Smarcb1; Smarcd1; Smarce1; Pou5f1; Sox2

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