smc2
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  • Official Full Name
  • structural maintenance of chromosomes 2
  • Background
  • Structural maintenance of chromosomes 2 (SMC2) and 4 (SMC4) proteins are subunits of the condensin complex, which enables chromosome condensation and maintains the compaction of chromosomes as they separate to opposite poles during anaphase (1-3). In addi
  • Synonyms
  • SMC2; structural maintenance of chromosomes 2; SMC2 (structural maintenance of chromosomes 2, yeast) like 1 , SMC2 structural maintenance of chromosomes 2 like 1 (yeast) , SMC2L1; structural maintenance of chromosomes protein 2; CAP E; hCAP E; SMC-2; SMC
Cat.#:SMC2-15610MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SMC2 Protein
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Cat.#:SMC2-6783CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SMC2
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Cat.#:SMC2-9947ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SMC2
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Involved Pathway

SMC2 involved in several pathways and played different roles in them. We selected most pathways SMC2 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, Condensation of Prometaphase Chromosomes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
RAD50; DYNC1I2; MCM9; CDC7; CDKN2B; SMAD3A; EP300; SMC3; NEK6; DSN1
Cell Cycle, Mitotic
CEP70; ENSA; NCAPD3; TUBGCP2; SETB; ZWINT; CLASP1A; STIL; CDCA8; NDEL1A
Condensation of Prometaphase Chromosomes
NCAPD2; CSNK2A1; CSNK2B; SMC2; SMC4; NCAPH; NCAPG; CSNK2A2
Condensation of Prophase Chromosomes
SETB; MCPH1; SMC4; PHF8; H3F3D; SETA; NCAPG2; SMC2; SET; NCAPD3
M Phase
SPDL1; SETA; ZWILCH; SETB; CENPN; CENPE; ARPP19; CDCA5; STAG1; SKA1
Mitotic Prometaphase
SGOL1; ZW10; CDCA8; CENPH; PDS5B; NSL1; SKA1; PANE1; NCAPH; SGOL2
Mitotic Prophase
TMEM188; VRK1; ENSAA; NCAPH2; CTDNEP1B; ARPP19B; CTDNEP1A; MCPH1; NEK7; SMC2

Protein Function

SMC2 has several biochemical functions, for example, ATP binding, nucleotide binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC2 itself. We selected most functions SMC2 had, and list some proteins which have the same functions with SMC2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PDK4; OAS2; UBE2L3B; ACSS1; RPS6KAL; MARK4; EPHB2; PRKAG2; FPGS; CCT6B
Function nucleotide binding
Related Protein CELF3A; RBMS2; DND1; GUCY2F; RPS6KAL; RHOGD; SMYHC2; STK35L; TRNAU1APA; DNAJC17
Function protein binding
Related Protein KRTAP5-6; GALT; CLTC; COL13A1; STAP1; RPIA; MAGEB4; PFKL; CERK; C8orf48
Function protein heterodimerization activity
Related Protein SMAD2; HIST2H2AA4; PIK3R1; SYT14; TIRAP; DMRTA2; TCF3; HOMER2; TAF12; NTSR1

Interacting Protein

SMC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC2.
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