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SMC6

Official Full Name

structural maintenance of chromosomes 6
Overview

Structural maintenance of chromosomes protein 6 is a protein that in humans is encoded by the SMC6 gene.
Synonyms

SMC6; structural maintenance of chromosomes 6; SMC6 structural maintenance of chromosomes 6 like 1 (yeast) , SMC6L1; structural maintenance of chromosomes protein 6; FLJ22116; SMC protein 6; SMC6 structural maintenance of chromosomes 6-like 1; SMC-6; hSMC;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SMC6-2812H	Recombinant Human SMC6, GST-tagged	E.coli	GST	740-1091aa	$319 / 25ug
Human	SMC6-1665HCL	Recombinant Human SMC6 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SMC6-5904H	Recombinant Human SMC6 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	SMC6-15614M	Recombinant Mouse SMC6 Protein	Mammalian Cell	His		Inquiry
Mouse	SMC6-8472M	Recombinant Mouse SMC6 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Smc6-5964M	Recombinant Mouse Smc6 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	SMC6-8472M-B	Recombinant Mouse SMC6 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

SMC6 involved in several pathways and played different roles in them. We selected most pathways SMC6 participated on our site, such as Metabolism of proteins, Post-translational protein modification, SUMO E3 ligases SUMOylate target proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Metabolism of proteins	TRAPPC1;MGAT4A;A4GNT;SMC5;ADAMTS10;SEC63;INHBAA;IGFALS;MLEC
Post-translational protein modification	PHC2;TRAPPC1;CBX8;NAPAB;CNIH2;TRAPPC9;GNE;ST8SIA3;NAPAA
SUMO E3 ligases SUMOylate target proteins	PHC1;CBX8;NSMCE2;RNF2;PHC3;SMC5;NSMCE1;SMC6;NSMCE4A
SUMOylation	RING1;RNF2;PHC3;NSMCE2;PHC1;NSMCE1;SCMH1;SENP1;EID3
SUMOylation of DNA damage response and repair proteins	SMC6;SMC5;NSMCE2;PHC2;RNF2;NSMCE1;PHC1;NSMCE4A;SCMH1

SMC6 has several biochemical functions, for example, ATP binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMC6 itself. We selected most functions SMC6 had, and list some proteins which have the same functions with SMC6. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	PFKM;KIF5A;GART;SNRKB;BCKDK;HSPH1;UBE2L3B;STK26;MOV10B.2
protein binding	LRP2BP;AP2M1;KDR;BAAT;RAB33B;IL2RG;LAMA4;SULT2B1;ZBP1
ubiquitin protein ligase binding	KDM4A;CUL3A;UBE2U;ARRB2;HSPA8;MOAP1;SCAMP3;PARK2;TRAF4

SMC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMC6.

NSMCE1; SMC5; NDNL2; NSMCE2