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SNTA1

Official Full Name

syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)
Overview

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes.
Synonyms

SNTA1; syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component); SNT1, syntrophin, alpha 1 (dystrophin associated protein A1, 59kD, acidic component); alpha-1-syntrophin; pro TGF alpha cytoplasmic domain interacting protein 1; TACIP1; 59 kDa dystrophin associated protein A1 acidic component 1; 59 kDa dystrophin-associated protein A1 acidic component 1; Acidic alpha 1 syntrophin; Alpha 1 syntrophin; dJ1187J4.5; Dystrophin associated protein A159kD acidic component; Dystrophin associated protein A1 59kDa acidic component; LQT12; OTTHUMP00000030650; Pro-TGF-alpha cytoplasmic domain-interacting protein 1; SNT 1; SNT1; SNTA 1; SNTA1_HUMAN; Syntrophin 1; Syntrophin alpha dystrophin associated protein A1 59kD acidic component; Syntrophin-1; Syntrophin1; TACIP 1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SNTA1-4831H	Recombinant Human Syntrophin, Alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component), His-tagged	E.coli	His		$179 / 10ug $498 / 50ug
Human	SNTA1-29288TH	Recombinant Human SNTA1, His-tagged	E.coli	His	505 amino acids	Inquiry
Human	SNTA1-1608HCL	Recombinant Human SNTA1 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SNTA1-6542H	Recombinant Human SNTA1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Snta1-6011M	Recombinant Mouse Snta1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rhesus Macaque	SNTA1-4385R	Recombinant Rhesus monkey SNTA1 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	SNTA1-4201R	Recombinant Rhesus Macaque SNTA1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	SNTA1-4201R-B	Recombinant Rhesus Macaque SNTA1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein

SNTA1 involved in several pathways and played different roles in them. We selected most pathways SNTA1 participated on our site, such as SIDS Susceptibility Pathways, Signaling mediated by p38-gamma and p38-delta, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNTA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
SIDS Susceptibility Pathways	SP3;PHOX2B;TPH2;MAP2;GATA2;POU3F2;EN1;MECP2;CHRFAM7A
Signaling mediated by p38-gamma and p38-delta

SNTA1 has several biochemical functions, for example, ATPase binding, PDZ domain binding, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNTA1 itself. We selected most functions SNTA1 had, and list some proteins which have the same functions with SNTA1. You can find most of the proteins on our site.

Function	Related Protein
ATPase binding	SDF2L1;DRD1A;RAB4A;WFS1;ATP1B1;ANK2;SLN;ALDOB;PKD2
PDZ domain binding	KCNJ4;PDZK1;SDC2;KIDINS220;DLG1;ACCN3;NKD1;ATP2B3A;CLCN3
actin binding	FHL3;VPS18;VMHC;SYNPO2L;LMOD2;SYNE1;MYO15;TPM4;AFAP1
calmodulin binding	C2orf62;TTN;AEBP1;CAMK4;ATP2B1;EPB41;PLCB1;RRAD;RASGRF2
ion channel binding	CAV1;CALM;CHERP;PRKCSH;FYN;PIRT;TCAP;YWHAE;KCNIP1
nitric-oxide synthase binding	DNM2;SCN5A;CAMK2D;DNM3;NOS1AP;CDH2;SLC6A4;ATP2B4;CD74
protein binding	CRY1A;RECQL4;HEMK1;UBE2B;TIMM10;CMKLR1;NRG1;CENPK;CARD10
contributes_to sodium channel regulator activity	SNTA1;ATP2B4
structural molecule activity	COPE;TUBA1C;CLDN1;LAMA3;MAP7D1B;KRT1-C5;CLDNK;LMNL3;KRT42

SNTA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNTA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SNTA1.

Mapk12; ABCA1; TFAP2A; XRCC6; Sstr2; UBE2V2; MED8