SOAT1
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Official Full Name
sterol O-acyltransferase 1
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Overview
Acyl-coenzyme A:cholesterol acyltransferase (ACACT; EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988 -
Synonyms
SOAT1; sterol O-acyltransferase 1; SOAT, STAT, sterol O acyltransferase (acyl Coenzyme A: cholesterol acyltransferase) 1; ACAT; acyl Coenzyme A: cholesterol acyltransferase; ACAT-1; ACAT1; Acyl coenzyme A cholesterol acyltransferase 1; Acyl-coenzyme A:cholesterol acyltransferase 1; Cholesterol acyltransferase 1; SOAT; SOAT1_HUMAN; STAT; Sterol O acyltransferase 1; OTTHUMP00000033188; acyl-Coenzyme A: cholesterol acyltransferase; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; ACACT; RP11-215I23.2;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
- Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
- Cynomolgus Monkey
- Homo sapiens (Human)
- Human
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | SOAT1-2868H | Recombinant Human SOAT1, GST-tagged | E.coli | GST | 1-326aa | |
Human | SOAT1-31430TH | Recombinant Human SOAT1 | Wheat Germ | N/A | 73 amino acids | |
Human | SOAT1-1665HCL | Recombinant Human SOAT1 cell lysate | N/A | |||
Mouse | SOAT1-15741M | Recombinant Mouse SOAT1 Protein | Mammalian Cell | His | ||
Mouse | SOAT1-8562M | Recombinant Mouse SOAT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Mouse | SOAT1-8562M-B | Recombinant Mouse SOAT1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rat | SOAT1-5660R | Recombinant Rat SOAT1 Protein | Mammalian Cell | His | ||
Rat | SOAT1-5319R | Recombinant Rat SOAT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | SOAT1-5319R-B | Recombinant Rat SOAT1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) | RFL3494CF | Recombinant Full Length Chlorocebus Aethiops Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-550) | |
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) | RFL22146CF | Recombinant Full Length Cricetulus Griseus Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-546) | |
Cynomolgus Monkey | SOAT1-955C | Recombinant Cynomolgus SOAT1 Protein, His-tagged | Mammalian Cell | His | ||
Cynomolgus Monkey | SOAT1-698C-B | Recombinant Cynomolgus Monkey SOAT1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Cynomolgus Monkey | SOAT1-698C | Recombinant Cynomolgus Monkey SOAT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Homo sapiens (Human) | RFL8317HF | Recombinant Full Length Human Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-550) | |
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) | RFL1727MF | Recombinant Full Length Macaca Fascicularis Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-550) | |
Mus musculus (Mouse) | RFL17435MF | Recombinant Full Length Mouse Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-540) | |
Rattus norvegicus (Rat) | RFL13920RF | Recombinant Full Length Rat Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged | E.coli expression system | His | Full Length (1-545) | |
Zebrafish | SOAT1-6662Z | Recombinant Zebrafish SOAT1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- SOAT1 Related Research Area
SOAT1 involved in several pathways and played different roles in them. We selected most pathways SOAT1 participated on our site, such as Steroid biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Steroid biosynthesis | NSDHL;CEL.1;CYP51;TM7SF2;MSMO1;Cel;SOAT2;SOAT1;HSD17B7 |
SOAT1 has several biochemical functions, for example, cholesterol O-acyltransferase activity, cholesterol binding, fatty-acyl-CoA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOAT1 itself. We selected most functions SOAT1 had, and list some proteins which have the same functions with SOAT1. You can find most of the proteins on our site.
Function | Related Protein |
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cholesterol O-acyltransferase activity | |
cholesterol binding | TSPO2;APOC3;APOF;CYP11A1;APOA4;ANXA6;OSBPL1A;STARD6;APOE |
fatty-acyl-CoA binding | PECI;ACOXL;HMGCL;ECI2;ACBD3;ALDH6A1;ACBD4;ACAD8;ACBD5A |
protein binding | MAFG;MKNK2;PDLIM2;RSPO2;TRIM43;KIF13B;RNASEL;RBFOX1;ZUFSP |
sterol O-acyltransferase activity | SOAT1;MBOAT4;NAT14;CML5;LPCAT3;MBOAT7;MBOAT1;CML2;Acnat1 |
SOAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOAT1.
TERF1; UBIAD1; Ktn1; Sec24c; KATNA1; Eef1a1; CANX; Rab5c; Bmpr1a; RAB5C; RAB7A; RAB2A; RAB11A; CLTC; PKN2; Rmdn3; TMEM63B; C1qbp
- Q&As
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