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SOAT1

  • Official Full Name

    sterol O-acyltransferase 1

  • Overview

    Acyl-coenzyme A:cholesterol acyltransferase (ACACT; EC 2.3.1.26) is an intracellular protein located in the endoplasmic reticulum that forms cholesterol esters from cholesterol. Accumulation of cholesterol esters as cytoplasmic lipid droplets within macrophages and smooth muscle cells is a characteristic feature of the early stages of atherosclerotic plaques (Cadigan et al., 1988
  • Synonyms

    SOAT1; sterol O-acyltransferase 1; SOAT, STAT, sterol O acyltransferase (acyl Coenzyme A: cholesterol acyltransferase) 1; ACAT; acyl Coenzyme A: cholesterol acyltransferase; ACAT-1; ACAT1; Acyl coenzyme A cholesterol acyltransferase 1; Acyl-coenzyme A:cholesterol acyltransferase 1; Cholesterol acyltransferase 1; SOAT; SOAT1_HUMAN; STAT; Sterol O acyltransferase 1; OTTHUMP00000033188; acyl-Coenzyme A: cholesterol acyltransferase; sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1; ACACT; RP11-215I23.2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
  • Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SOAT1-2868H Recombinant Human SOAT1, GST-tagged E.coli GST 1-326aa
Human SOAT1-31430TH Recombinant Human SOAT1 Wheat Germ N/A 73 amino acids
Human SOAT1-1665HCL Recombinant Human SOAT1 cell lysate N/A
Mouse SOAT1-15741M Recombinant Mouse SOAT1 Protein Mammalian Cell His
Mouse SOAT1-8562M Recombinant Mouse SOAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SOAT1-8562M-B Recombinant Mouse SOAT1 Protein Pre-coupled Magnetic Beads HEK293
Rat SOAT1-5660R Recombinant Rat SOAT1 Protein Mammalian Cell His
Rat SOAT1-5319R Recombinant Rat SOAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SOAT1-5319R-B Recombinant Rat SOAT1 Protein Pre-coupled Magnetic Beads HEK293
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) RFL3494CF Recombinant Full Length Chlorocebus Aethiops Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged E.coli expression system His Full Length (1-550)
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) RFL22146CF Recombinant Full Length Cricetulus Griseus Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged E.coli expression system His Full Length (1-546)
Cynomolgus Monkey SOAT1-955C Recombinant Cynomolgus SOAT1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey SOAT1-698C-B Recombinant Cynomolgus Monkey SOAT1 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey SOAT1-698C Recombinant Cynomolgus Monkey SOAT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL8317HF Recombinant Full Length Human Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged E.coli expression system His Full Length (1-550)
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) RFL1727MF Recombinant Full Length Macaca Fascicularis Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged E.coli expression system His Full Length (1-550)
Mus musculus (Mouse) RFL17435MF Recombinant Full Length Mouse Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged E.coli expression system His Full Length (1-540)
Rattus norvegicus (Rat) RFL13920RF Recombinant Full Length Rat Sterol O-Acyltransferase 1(Soat1) Protein, His-Tagged E.coli expression system His Full Length (1-545)
Zebrafish SOAT1-6662Z Recombinant Zebrafish SOAT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SOAT1 Related Research Area

SOAT1 involved in several pathways and played different roles in them. We selected most pathways SOAT1 participated on our site, such as Steroid biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOAT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Steroid biosynthesisNSDHL;CEL.1;CYP51;TM7SF2;MSMO1;Cel;SOAT2;SOAT1;HSD17B7

SOAT1 has several biochemical functions, for example, cholesterol O-acyltransferase activity, cholesterol binding, fatty-acyl-CoA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOAT1 itself. We selected most functions SOAT1 had, and list some proteins which have the same functions with SOAT1. You can find most of the proteins on our site.

Function Related Protein
cholesterol O-acyltransferase activity
cholesterol bindingTSPO2;APOC3;APOF;CYP11A1;APOA4;ANXA6;OSBPL1A;STARD6;APOE
fatty-acyl-CoA bindingPECI;ACOXL;HMGCL;ECI2;ACBD3;ALDH6A1;ACBD4;ACAD8;ACBD5A
protein bindingMAFG;MKNK2;PDLIM2;RSPO2;TRIM43;KIF13B;RNASEL;RBFOX1;ZUFSP
sterol O-acyltransferase activitySOAT1;MBOAT4;NAT14;CML5;LPCAT3;MBOAT7;MBOAT1;CML2;Acnat1

SOAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOAT1.

TERF1; UBIAD1; Ktn1; Sec24c; KATNA1; Eef1a1; CANX; Rab5c; Bmpr1a; RAB5C; RAB7A; RAB2A; RAB11A; CLTC; PKN2; Rmdn3; TMEM63B; C1qbp

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