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SORCS3

Official Full Name

sortilin-related VPS10 domain containing receptor 3
Overview

This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. Two of the five family members (sortilin and sortilin-related receptor) are synthesized as preproproteins; it is not yet known if this encoded protein is also a preproprotein.
Synonyms

SORCS3; sortilin-related VPS10 domain containing receptor 3; VPS10 domain-containing receptor SorCS3; KIAA1059; SORCS; 6330404A12Rik; RP11 107L7.1; SORC3_HUMAN; SORCS 3; Sortilin related VPS10 domain containing receptor 3; VPS10 domain containing receptor SorCS3; VPS10 domain receptor protein SORCS 3; OTTHUMP00000020444; VPS10 domain receptor protein SORCS 3 (SORCS3); RP11-107L7.1;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SORCS3-786H	Recombinant Human SORCS3	Mammalian Cell	His	Inquiry
Human	SORCS3-1670HCL	Recombinant Human SORCS3 cell lysate		N/A	Inquiry
Human	SORCS3-4104H	Recombinant Human SORCS3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Human	SORCS3-4104H-B	Recombinant Human SORCS3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SORCS3 Related Research Area

SORCS3 involved in several pathways and played different roles in them. We selected most pathways SORCS3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SORCS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

SORCS3 has several biochemical functions, for example, neuropeptide receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SORCS3 itself. We selected most functions SORCS3 had, and list some proteins which have the same functions with SORCS3. You can find most of the proteins on our site.

Function	Related Protein
neuropeptide receptor activity	PRLHR;NPFFR1L1;NPFFR1L3;SORCS2;NPFFR1;KISS1RA;NMUR1;NPBWR1;NPFFR2

SORCS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SORCS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SORCS3.

NGF

VPS10P-domain Family