sox1
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  • Official Full Name
  • SRY (sex determining region Y)-box 1
  • Background
  • This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development. [provided by RefSeq, Jul 2008]
  • Synonyms
  • SOX1; SRY (sex determining region Y)-box 1; transcription factor SOX-1; SRY-related HMG-box gene 1;
Cat.#:SOX1-5905CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SOX1
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Cat.#:SOX1-1566HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SOX1 293 Cell Lysate
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Involved Pathway

SOX1 involved in several pathways and played different roles in them. We selected most pathways SOX1 participated on our site, such as Cardiac Progenitor Differentiation, Wnt Signaling Pathway NetPath, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cardiac Progenitor Differentiation
NKX2; IRX4; TBX20; ZFP42; BMP1; TBX5; SOX1; SIRPA; ROR2; T
Wnt Signaling Pathway NetPath
MTAP1B; SALL1; MARK2; HIPK2; BCL9; ROR2; PAX2; CRYBB2; BRD7; SOX1

Protein Function

SOX1 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, core promoter sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX1 itself. We selected most functions SOX1 had, and list some proteins which have the same functions with SOX1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ASCL5; KDM2B; PPP1R8; KDM5A; ZBTB20; POU3F3; AHCTF1; GPBP1L1; HNRPK; TGIF2LX
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein RBPJA; MEF2A; CTCF; NFATC2; CEBPA; HELT; RFX4; CLOCK; FEZF1; BCL11B
Function core promoter sequence-specific DNA binding
Related Protein ZFP932; SP1; NFYA; MEOX1; GATA3; PROX1; CREM; SOX4; THRAP3; ESR2
Function protein binding
Related Protein TRAPPC2; COPS3; NMI; CTDSP1; TDGF1; RAB5B; MRTO4; NFKB2; SPSB1; MAGI2
Function transcription factor activity, sequence-specific DNA binding
Related Protein SALL3B; IRF2; HOXB3A; ZKSCAN6; ELK4; ZFP191; TTC4; SOX4; CNBP; ZFP639
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein CEBPG; DDIT3; NOBOX; NEUROD6; ARNT2; NFATC2; STAT3; POU2F3; EBF3A; ELF4

Interacting Protein

SOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX1.
STAT3

SOX1 Related Articles

Horta, ES; Lennon, VA; et al. Neural Autoantibody Clusters Aid Diagnosis of Cancer. CLINICAL CANCER RESEARCH 20:3862-3869(2014).
Evoli, A; Liguori, R; et al. Italian recommendations for Lambert-Eaton myasthenic syndrome (LEMS) management. NEUROLOGICAL SCIENCES 35:515-520(2014).