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SOX13

  • Official Full Name

    SRY (sex determining region Y)-box 13

  • Overview

    This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. It has also been determined to be a type-1 diabetes autoantigen, also known as islet cell antibody 12.
  • Synonyms

    SOX13; SRY (sex determining region Y)-box 13; transcription factor SOX-13; ICA12; islet cell 12; MGC117216; Sox 13; SRY box 13; SRY related HMG box gene 13; type 1 diabetes autoantigen; SRY-box 13; islet cell antigen 12; SRY-related HMG-box gene 13; type 1 diabetes autoantigen ICA12; Sox-13;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Arg
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SOX13-2881H Recombinant Human SOX13, GST-tagged E.coli GST 1-301aa
Human SOX13-138H Recombinant Human SOX13 protein, Arginine-tagged E.coli Arg
Human SOX13-1563HCL Recombinant Human SOX13 293 Cell Lysate HEK293 N/A
Human SOX13-5063H Recombinant Human SOX13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SOX13-1811HFL Recombinant Full Length Human SOX13 Protein, C-Flag-tagged Mammalian cells Flag
Human SOX13-2073H-B Recombinant Human SOX13 Protein Pre-coupled Magnetic Beads HEK293
Human SOX13-2073H Recombinant Human SOX13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SOX13-15775M Recombinant Mouse SOX13 Protein Mammalian Cell His
Mouse SOX13-8586M Recombinant Mouse SOX13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Sox13-6050M Recombinant Mouse Sox13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SOX13-8586M-B Recombinant Mouse SOX13 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SOX13 involved in several pathways and played different roles in them. We selected most pathways SOX13 participated on our site, such as Deactivation of the beta-catenin transactivating complex, Signal Transduction, Signaling by Wnt, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Deactivation of the beta-catenin transactivating complexPYGO2;TLE4;SOX7;PYGO1;SOX13;BCL9;TLE3B;CBY1;SOX9A
Signal TransductionDLK1;ZNRF3;CRABP1B;ROPN1;RLN3;OR52J3;HHAT;MYO7AA;ARHGEF17
Signaling by WntLGR6;RSPO2;FMNL3;ROR1;AES;PRICKLE1;KLHL12;ZNRF3;TMED5
TCF dependent signaling in response to WNTTLE3B;PYGO1;SOX9B;TNKS;SRY;TNKS2;LGR4;SOX7;ZNRF3

SOX13 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding, protein binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX13 itself. We selected most functions SOX13 had, and list some proteins which have the same functions with SOX13. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II regulatory region sequence-specific DNA bindingZBTB16A;POGZA;ZFY1;DMRT1;PLAGL1;GATA2B;ACTN4;ZFP551;LEF1
protein bindingAGXT;DCAF12L1;RPL7A;TAF1D;TIMP2;TBCD;TICAM1;ANKS4B;RSU1
sequence-specific DNA bindingFOXD4L1;PPARA;FOXD1L;GATA2B;ATF5A;PRDM5;FOXB1A;KLF5;FOXN2
transcription factor activity, sequence-specific DNA bindingNFYC;TBR1B;ZNF205;L3MBTL4;PLAGX;AHR;MAFG;YBX1;ZNF92

SOX13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX13 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX13.

CTBP2; SMAD7; YTHDC1

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