SOX17
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Official Full Name
SRY (sex determining region Y)-box 17
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Overview
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. -
Synonyms
SOX17; SRY (sex determining region Y)-box 17; transcription factor SOX-17; SOX17_HUMAN; SRY (sex determining region Y) box 17; SRY box 17; SRY related HMG box transcription factor SOX17; Transcription factor SOX17; OTTHUMP00000226577; SRY-related HMG-box transcription factor SOX17; VUR3;
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- SOX17 Related Articles
- SOX17 Related Research Area
SOX17 involved in several pathways and played different roles in them. We selected most pathways SOX17 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SOX17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Wnt signaling pathway | CCND2;CUL1;PLCB1;TLE3A;PPARDB;AXIN2;CCND2A;BTRC;PPP3CCB |
SOX17 has several biochemical functions, for example, beta-catenin binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SOX17 itself. We selected most functions SOX17 had, and list some proteins which have the same functions with SOX17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| beta-catenin binding | SHROOM2;SMAD7;TCF7L1A;PSEN1;BCL9;KLF4;DACT1;SOX17;BTRC |
| protein binding | ITPR3;MAP1LC3B;MARCKSL1;MYOG;MAF;AFG3L2;GADD45B;TPD52;MAPK7 |
| protein heterodimerization activity | BAK1;DRAP1;RELA;UGT1A3;ADRB1;HIST1H2BH;CEBPB;PRSS28;FLOT1 |
| sequence-specific DNA binding | HOXD10A;GRHL2A;RORA;SOX14;ATF7A;NOTCH1;POU2F3;HOXB3A;IRX5 |
| transcription coactivator activity | GTF2F1;ASXL1;SUB1B;NRIP1;ZSCAN1;SOX17;TRIM24;ATF6;LPIN3 |
| transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | SRF;CIR1;USF1;PTH;SRY;GTF2IRD1;AHR;FOXC1;MYOG |
| transcription factor binding | E2F4;MLXIPL;CTNNB1;CCND1;WWP2;KEAP1B;PPP1R13BB;TWIST1;TAF12 |
| transcription regulatory region DNA binding | TP73;KLF17;GFI1;RELA;TA;IKZF1;IKZF4;GLIS2;GLI1 |
| transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | IRF2;MAFGA;FOXF1;MAFGB;GATA2A;CSRNP2;FOXF2;PAX9;SLAMF7 |
SOX17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SOX17 here. Most of them are supplied by our site. Hope this information will be useful for your research of SOX17.
CTNNB1; EEFSEC; RPL38; Sox17; EBNA1BP2; HOMER3
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