spink5
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  • Official Full Name
  • serine peptidase inhibitor, Kazal type 5
  • Background
  • This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • SPINK5; serine peptidase inhibitor, Kazal type 5; serine protease inhibitor, Kazal type 5; serine protease inhibitor Kazal-type 5; DKFZp686K19184; FLJ21544; FLJ97536; FLJ97596; FLJ99794; LEKTI; LETKI; lymphoepithelial Kazal type related inhibitor; NETS; N
Cat.#:SPINK5-686HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SPINK5 Protein, His-tagged
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Cat.#:Spink5-687MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Spink5 Protein, His-tagged
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Cat.#:Spink5-688MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Spink5 Protein, His/GST-tagged
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SPINK5 Related Articles

Aizawa, S; Ochiai, T; et al. Heterogeneous and abnormal localization of desmosomal proteins in oral intraepithelial neoplasms. JOURNAL OF ORAL SCIENCE 56:209-214(2014).
Fortugno, P; Bresciani, A; et al. Proteolytic Activation Cascade of the Netherton Syndrome-Defective Protein, LEKTI, in the Epidermis: Implications for Skin Homeostasis. JOURNAL OF INVESTIGATIVE DERMATOLOGY 131:2223-2232(2011).