Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

SRGN

  • Official Full Name

    serglycin

  • Overview

    This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.
  • Synonyms

    SRGN; serglycin; PRG, PRG1, proteoglycan 1, secretory granule; PPG; serglycin proteoglycan; Chondroitin sulfate proteoglycan core protein; Cytolytic granule proteoglycan core protein; FLJ12930; gp600; Hematopoetic proteoglycan core protein; Mastocytoma proteoglycan core protein; MGC9289; OTTHUMP00000019716; P.PG; PG19 core protein; Pgsg; Platelet proteoglycan core protein; platelet proteoglycan protein core; PRG; PRG1; PROTEOGLYCAN 1; proteoglycan 1, secretory granule; Proteoglycan 10K core protein; Proteoglycan peptide core protein; PROTEOGLYCAN PROTEIN CORE FOR MAST CELL SECRETORY GRANULE; secretory granule proteoglycan 1; Secretory granule proteoglycan core protein; Sgc; SRGN_HUMAN; hematopoetic proteoglycan core peptide; secretory granule proteoglycan core peptide; secreto;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Protein Conjugation
  • Wheat Germ
  • C
  • His
  • GST
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SRGN-6884H Recombinant Human Serglycin, His-tagged E.coli His 28-158aa
Human SRGN-31460TH Recombinant Human SRGN Wheat Germ N/A 66 amino acids
Human SRGN-31396TH Recombinant Human SRGN, His-tagged E.coli His 131 amino acids
Human SRGN-31397TH Recombinant Human SRGN Wheat Germ N/A 158 amino acids
Human SRGN-2952H Recombinant Human SRGN, GST-tagged E.coli GST 23-158aa
Human SRGN-513H Recombinant Human SRGN, His tagged Human Cell His
Human SRGN-1119HCL Recombinant Human SRGN cell lysate Human Cell N/A
Human SRGN-2734H Recombinant Human SRGN Protein, His-tagged E.coli N-His Tyr28-Leu158
Human SRGN-2836H Recombinant Human SRGN Protein, His-tagged, OVA Conjugated Protein Conjugation N-His Asp119-Gly148
Human SRGN-5977H Recombinant Human SRGN Protein (Gly27-Leu158), N-His tagged Mammalian cells N-His Gly27-Leu158
Human SRGN-494HF Recombinant Full Length Human SRGN Protein In Vitro Cell Free System 158 amino acids
Human SRGN-2624H Recombinant Human SRGN protein(81-150 aa), C-His-tagged E. coli C-His 81-150 aa
Mouse SRGN-15982M Recombinant Mouse SRGN Protein Mammalian Cell His
Mouse Srgn-8125M Recombinant Mouse Srgn protein, His-tagged E.coli His Ala28~Ile152 (Accession # P13609)
Mouse SRGN-8716M Recombinant Mouse SRGN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SRGN-8716M-B Recombinant Mouse SRGN Protein Pre-coupled Magnetic Beads HEK293
Rat SRGN-5741R Recombinant Rat SRGN Protein Mammalian Cell His
Rat SRGN-5400R-B Recombinant Rat SRGN Protein Pre-coupled Magnetic Beads HEK293
Rat Srgn-2104R Recombinant Rat Srgn Protein, His&GST-tagged E.coli N-His&GST Arg76-Ile179
Rat SRGN-5400R Recombinant Rat SRGN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SRGN-4464R Recombinant Rhesus monkey SRGN Protein, His-tagged Mammalian Cell His
Rhesus Macaque SRGN-4280R Recombinant Rhesus Macaque SRGN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SRGN-4280R-B Recombinant Rhesus Macaque SRGN Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SRGN-7672Z Recombinant Zebrafish SRGN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SRGN Related Research Area

SRGN involved in several pathways and played different roles in them. We selected most pathways SRGN participated on our site, such as Hemostasis, Platelet activation, signaling and aggregation, Platelet degranulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRGN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
HemostasisCEACAM1;ABHD6B;OSTN;ATP2B3A;DOK2;MFN1;DGKG;F9B;STXBP3
Platelet activation, signaling and aggregationPDPN;SRGN;CLU;IGF2B;GAS6;MMRN1;C6orf25;STXBP3;G6b
Platelet degranulationHRG;CD9A;SRGN;TFA;MMRN1;CD9B;F13A1A.1;CAP1;SPARC
Response to elevated platelet cytosolic Ca2+STXBP3A;BRPF3;PLEK;STXBP3;SERPINF2B;MMRN1;IGF2B;MMRN2A;WDR1

SRGN has several biochemical functions, for example, collagen binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SRGN itself. We selected most functions SRGN had, and list some proteins which have the same functions with SRGN. You can find most of the proteins on our site.

Function Related Protein
collagen bindingDDR1;TGFBI;ITGA3;PAK1;GPR56;CTSB;PODN;ACHE;DDR2
protein bindingZMAT4;HDHD3;NAA50;BLOC1S2;SEC23A;BTF3L4;HGS;C8orf4;WDHD1

SRGN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRGN here. Most of them are supplied by our site. Hope this information will be useful for your research of SRGN.

SGTA; UBQLN1; UBQLN1; GZMB; VCAN; MMP9; cabc1_provu; PRF1; caf1M; FHL3; q5nem9_fratt

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All SRGN Products

Required fields are marked with *

My Review for All SRGN Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends