stard8
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  • Official Full Name
  • StAR-related lipid transfer (START) domain containing 8
  • Background
  • This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor.
  • Synonyms
  • STARD8; StAR-related lipid transfer (START) domain containing 8; START domain containing 8; stAR-related lipid transfer protein 8; ARHGAP38; KIAA0189; Deleted in liver cancer 3; DLC3; StAR related lipid transfer protein 8; START domain containing protein 8; START GAP3; deleted in liver cancer 3 protein; STARTGAP3
Cat.#:STARD8-16106MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse STARD8 Protein
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Cat.#:STARD8-6765ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish STARD8
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Cat.#:STARD8-1708HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human STARD8 cell lysate
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Involved Pathway

STARD8 involved in several pathways and played different roles in them. We selected most pathways STARD8 participated on our site, such as Rho GTPase cycle, Signal Transduction, Signaling by Rho GTPases, which may be useful for your reference. Also, other proteins which involved in the same pathway with STARD8 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Rho GTPase cycle
RHOU; ARHGAP26; ARHGAP29; STARD13; ARAP2; RALBP1; ARHGAP1; ARHGAP17A; TAGAPA; ARHGAP22
Signal Transduction
ADM2; FSTL1B; OXGR1A.2; CXCL11.8; CHN1; ADH8B; CGNB; RBCK1; KLHL12; GPR132
Signaling by Rho GTPases
ARHGAP6; ARHGAP24; MKL1; FGD4A; TAX1BP3; FMNL1; ARHGAP12B; ARHGEF17; RHOU; ARHGAP10

Protein Function

STARD8 has several biochemical functions, for example, GTPase activator activity, lipid binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STARD8 itself. We selected most functions STARD8 had, and list some proteins which have the same functions with STARD8. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activator activity
Related Protein ERRFI1; NIPAL1; RGS4; ELMOD1; TBC1D15; ACAP3; ARHGAP27; SMAP2; DOCK1; SRGAP2A
Function lipid binding
Related Protein PTGS2; VCP; DNM1L; RBP2B; ANXA6; APOL2; FABP1B.1; FABP9; PTEN; BAIAP2L2B

STARD8 Related Articles

Holeiter, G; Bischoff, A; et al. The RhoGAP protein Deleted in Liver Cancer 3 (DLC3) is essential for adherens junctions integrity. ONCOGENESIS 1:-(2012).
Petit, F; Andrieux, J; et al. Xq12q13.1 microduplication encompassing the EFNB1 gene in a boy with congenital diaphragmatic hernia. EUROPEAN JOURNAL OF MEDICAL GENETICS 54:E525-E527(2011).