stx4
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  • Official Full Name
  • syntaxin 4
  • Background
  • Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
  • Synonyms
  • STX4; syntaxin 4; STX4A, syntaxin 4A (placental); syntaxin-4; p35 2; NY REN 31 antigen; Renal carcinoma antigen NY REN 31; Renal carcinoma antigen NY-REN-31; STX4_HUMAN; STX4A; Syntaxin 4A; syntaxin 4A (placental); p35-2
Cat.#:STX4-3030HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human STX4, His-tagged
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Cat.#:STX4-31439THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human STX4
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Cat.#:STX4-5814RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat STX4 Protein
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Cat.#:STX4-10561ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish STX4
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Cat.#:STX4-1375HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human STX4 293 Cell Lysate
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Involved Pathway

STX4 involved in several pathways and played different roles in them. We selected most pathways STX4 participated on our site, such as SNARE interactions in vesicular transport, Vasopressin-regulated water reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with STX4 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SNARE interactions in vesicular transport
STX7; STX11A; STX6; SNAP23.1; YKT6; BET1; SEC22BB; STX2A; GOSR2; STX2
Vasopressin-regulated water reabsorption
DYNC1LI1; CREB3L3; CREB3L2; DYNC1LI2; AQP3; CREB3L1; AQP2; DYNC1I1; RAB5B; STX4

Protein Function

STX4 has several biochemical functions, for example, SNAP receptor activity, SNARE binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STX4 itself. We selected most functions STX4 had, and list some proteins which have the same functions with STX4. You can find most of the proteins on our site.
Function
Related Protein
Function SNAP receptor activity
Related Protein SNAP25B; SEC22BA; SNAP23.2; STX4; SNAP47; SNAP23; VAMP8; STX18; STX16; SNAP25A
Function SNARE binding
Related Protein LRRK2; SEC22BA; VAMP5; SNAPIN; EXOC3L4; STX2A; GOSR2; VTI1A; STX1B; TNFAIP2
Function protein binding
Related Protein TNIP2; ITGA6; P4HA1; AGR2; CHMP4A; CRYGC; GADD45B; RPLP2; S100A7; TMPO
Function sphingomyelin phosphodiesterase activator activity
Related Protein STX4A; STX4

Interacting Protein

STX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of STX4.
VAMP3; STX7; STX6; VAMP4; CYBRD1