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STXBP3

Official Full Name

syntaxin binding protein 3
Overview

Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Synonyms

STXBP3; syntaxin binding protein 3; syntaxin-binding protein 3; UNC 18C; Munc18 3; Munc18 c; Platelet Sec1 protein; Protein unc-18 homolog 3; Protein unc-18 homolog C; PSP; STXB3_HUMAN; STXBP 3; Sxtbp3; syntaxin 4 binding protein; Unc 18 3; Unc 18 homolog 3; Unc-18C; Unc18-3; MUNC18C; MUNC18-3;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Insect Cell
Insect Cells
Mammalian Cell

Tag

His
GST
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	STXBP3-3786H	Recombinant Human STXBP3 protein, His&GST-tagged	Insect Cells	His/GST	Met1-Glu592	$498 / 20 µg
Human	STXBP3-3036H	Recombinant Human STXBP3, His-tagged	E.coli	His	242-592aa	$319 / 25ug
Human	STXBP3-600HCL	Recombinant Human STXBP3 cell lysate	Insect Cell	N/A		Inquiry
Human	STXBP3-2986H	Recombinant Human STXBP3 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	STXBP3-5935H	Recombinant Human STXBP3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Stxbp3-6210M	Recombinant Mouse Stxbp3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	STXBP3-12639Z	Recombinant Zebrafish STXBP3	Mammalian Cell	His		Inquiry
Chicken	STXBP3-3567C	Recombinant Chicken STXBP3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
STXBP3 Related Articles
STXBP3 Related Research Area

STXBP3 involved in several pathways and played different roles in them. We selected most pathways STXBP3 participated on our site, such as Disinhibition of SNARE formation, Hemostasis, Insulin Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with STXBP3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Disinhibition of SNARE formation	STXBP3A;STXBP3
Hemostasis	CXADR;SLC16A8;KIF3B;DOCK2;CALU;RHOGA;F9A;ITGB3A;MERTK
Insulin Signaling	MAPK4;CAP1;MAP4K5;RHOJ;STXBP2;RRAD;ARHGAP33;KIF5B;MAPK6
Membrane Trafficking	TCEAL4;GJB2;SNX9;DAB2;CLINT1;NSFA;LMAN2L;COPG;PICALMB
Platelet activation, signaling and aggregation	AASS;F13A1B;SRGN;TFA;CD9A;WDR1;CLEC1B;GAS6;G6b
Response to elevated platelet cytosolic Ca2+	MMRN1;STXBP3A;F13A1B;IGF2B;SCG3;PLEK;MMRN2A;SRGN;CD9A
Translocation of GLUT4 to the plasma membrane	RALAA;RAB10;MYO1C;RALAB;STXBP3
Vesicle-mediated transport	TRAPPC2L;COPB1;AP1S3A;NAPB;GJA8;TRAPPC2;FTH1A;SNAPIN;ARCN1B

STXBP3 has several biochemical functions, for example, protein binding, syntaxin binding, syntaxin-1 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STXBP3 itself. We selected most functions STXBP3 had, and list some proteins which have the same functions with STXBP3. You can find most of the proteins on our site.

Function	Related Protein
protein binding	APBB1IP;FAM192A;COPS2;PCSK2;ATP5O;ARHGDIA;UGP2;TNS4;NUDT4
syntaxin binding	STX7;CAV1;TXLNBB;CPLX3A;CPLX2;VAMP2;STXBP4;SNAP23.1;STXBP5A
syntaxin-1 binding	MYO5A;CCDC167;VAMP2;CPLX1;NSF;STXBP3;STXBP2;SLC6A4;RNF40

STXBP3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STXBP3 here. Most of them are supplied by our site. Hope this information will be useful for your research of STXBP3.

RPL3; katG; pi3p; FN1

Rodriguez, AR; Muller, LPD; et al. The RNA binding protein RBPMS is a selective marker of ganglion cells in the mammalian retina. JOURNAL OF COMPARATIVE NEUROLOGY 522:1411-1443(2014).

Zhang, Y; Kang, YH; et al. Cab45b, a Munc18b-interacting Partner, Regulates Exocytosis in Pancreatic beta-Cells. JOURNAL OF BIOLOGICAL CHEMISTRY 284:20840-20847(2009).

Synaptic SNAREs