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SYNE2

  • Official Full Name

    spectrin repeat containing, nuclear envelope 2

  • Overview

    The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    SYNE2; spectrin repeat containing, nuclear envelope 2; nesprin-2; DKFZP434H2235; KIAA1011; Nesprin 2; NUA; NUANCE; SYNE 2; DKFZp686E01115; DKFZp686H1931; FLJ11014; FLJ43727; FLJ45710; FLJ46790; Nesprin2; Nuclear envelope spectrin repeat protein 2; Nucleus and actin connecting element; Nucleus and actin connecting element protein; Protein NUANCE; Spectrin repeat containing nuclear envelope 2; Synaptic nuclear envelope protein 2; Synaptic nuclei expressed gene 2; polytrophin; OTTHUMP00000179075; OTTHUMP00000245231; OTTHUMP00000245355; OTTHUMP00000245357; OTTHUMP00000245358; nucleus and acti; EDMD5; TROPH; SYNE-2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SYNE2-3047H Recombinant Human SYNE2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SYNE2-1644H Recombinant Human SYNE2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SYNE2-376H Recombinant Human SYNE2 Protein, His-tagged E.coli His Glu6~Gln296
Human SYNE2-5767H Recombinant Human SYNE2 Protein (Glu6-Ala264), His tagged E.coli His Glu6-Ala264
Human SYNE2-5768H Recombinant Human SYNE2 Protein (Glu6-Asp263), N-His tagged E.coli N-His Glu6-Asp263
Mouse SYNE2-16308M Recombinant Mouse SYNE2 Protein Mammalian Cell His
Mouse SYNE2-8910M Recombinant Mouse SYNE2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SYNE2-8910M-B Recombinant Mouse SYNE2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SYNE2 involved in several pathways and played different roles in them. We selected most pathways SYNE2 participated on our site, such as Meiotic Synapsis, Mus musculus biological processes, Ovarian Infertility Genes, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYNE2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Meiotic SynapsisTERF2;SYCE2;SYCP2;FKBP6;TERF2IP;TEX12;TINF2;POT1A;TERF1
Mus musculus biological processesSYCP1;SYNE2;MED11;SYCE2;POT1A;KLF5;SUN2
Ovarian Infertility GenesNRIP1;ZP2;SYNE2;INHA;MSH5;DMC1;ZP3;DAZL;GJA4

SYNE2 has several biochemical functions, for example, actin binding, actin filament binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYNE2 itself. We selected most functions SYNE2 had, and list some proteins which have the same functions with SYNE2. You can find most of the proteins on our site.

Function Related Protein
actin bindingHOOK1;YWHAH;NEXN;SPNA1;CNN3B;MYBPC2;WASF1;ACE;CYFIP1
actin filament bindingWIPF1;TRIOBPB;SHROOM4;PLDN;PPP1R9B;CORO6;LASP1;KLHL17;SLC6A4

SYNE2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYNE2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYNE2.

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