SYNJ1
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Official Full Name
synaptojanin 1
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Overview
has inositol 5-phosphatase activity; interacts with dynamin to play a role in synaptic vesicle recycling [RGD, Feb 2006] -
Synonyms
SYNJ1; synaptojanin 1; synaptojanin-1; synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 1;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Zebrafish
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- Myc|DDK
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | SYNJ1-3073H | Recombinant Human SYNJ1 Protein, MYC/DDK-tagged | HEK293 | Myc/DDK | ||
Human | SYNJ1-3074H | Active Recombinant Human SYNJ1 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | Synj1-247M | Recombinant Mouse Synj1 Protein, MYC/DDK-tagged | HEK293T | MYC/DDK | ||
Rat | SYNJ1-5868R | Recombinant Rat SYNJ1 Protein | Mammalian Cell | His | ||
Rat | SYNJ1-5527R | Recombinant Rat SYNJ1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | SYNJ1-5527R-B | Recombinant Rat SYNJ1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | SYNJ1-1617Z | Recombinant Zebrafish SYNJ1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
SYNJ1 involved in several pathways and played different roles in them. We selected most pathways SYNJ1 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with SYNJ1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Inositol phosphate metabolism | TPI1B;MINPP1;INPP5L;IMPA1;NUDT3A;PI4KA;PIK3CG;PIK3C2G;MTMR14 |
Metabolic pathways | CYP26B1;ST6GALNAC5;HADHAB;AOX3L1;ACSM1;DHDPSL;PIGF;AK4;AGXT2L1 |
Phosphatidylinositol signaling system | PIP4K2A;IP6K3;CALM1B;SYNJ1;PLCG1;IP6K2;CALM3;PLCB4;PIK3CB |
SYNJ1 has several biochemical functions, for example, hydrolase activity, nucleic acid binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SYNJ1 itself. We selected most functions SYNJ1 had, and list some proteins which have the same functions with SYNJ1. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
hydrolase activity | ATP6V0E;KLK1B9;THSD4;NUDT17;PTPRNA;METAP2A;CTSM;RHOT1B;FAM105B |
nucleic acid binding | ZFP423;ZRANB3;BCL6A;KHDRBS1B;ARL14EP;ZCCHC10;ZFP637;PTBP1A;PTBP2B |
nucleotide binding | MAP2K2B;MYHZ1.1;STK26;RBM47;CKMT2A;CAMK1DA;DAZL;DCLK3;CMPK |
phosphatidylinositol phosphate 4-phosphatase activity | |
phosphatidylinositol phosphate 5-phosphatase activity | SYNJ1;INPP5K |
phosphoric ester hydrolase activity | SYNJ1;FBP1B;SACM1LA;EXO5;SACM1L;REXO1;RNASEKB;ZRANB3;TMPPE |
SYNJ1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SYNJ1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SYNJ1.
- Q&As
- Reviews
Q&As (5)
Ask a questionSYNJ1 is primarily expressed in the nervous system, emphasizing its role in neuronal function and synaptic transmission.
SYNJ1 dysfunction may lead to impaired synaptic vesicle recycling, disrupting normal neurotransmission and contributing to synaptic dysfunction observed in neurodegenerative diseases.
Research is underway to explore the feasibility of detecting SYNJ1 alterations in cerebrospinal fluid or blood as potential diagnostic or prognostic markers for neurodegenerative diseases.
SYNJ1 mutations are thought to disrupt synaptic vesicle endocytosis, leading to impaired neurotransmitter release and contributing to the pathogenesis of Parkinson's disease.
Customer Reviews (3)
Write a reviewThis protein, manufactured with utmost precision, provides reliable and consistent results, ensuring the accuracy and reproducibility of your research findings.
Its purity and functional integrity guarantee optimal performance in a wide range of experimental applications.
Their team of experts is readily available to assist you with any inquiries or challenges you may encounter during your experiments.
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