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SCD1

Official Full Name

stearoyl-Coenzyme A desaturase 1
Synonyms

SCD1; stearoyl-Coenzyme A desaturase 1; acyl-CoA desaturase 1; STOMATAL CYTOKINESIS-DEFECTIVE 1; asebia; delta-9 desaturase 1; delta(9)-desaturase 1; fatty acid desaturase 1; stearoyl-CoA desaturase 1; ab; Scd; Scd-1; AA589638; AI265570;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Mouse
Mus musculus (Mouse)
Rat
Rattus norvegicus (Rat)

Source

E.coli
E.coli expression system
E.Coli or Yeast
HEK293
In vitro E. coli expression system
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Mouse	Scd1-3127M	Recombinant Mouse Scd1, His-tagged	E.Coli or Yeast	His	355	Inquiry
Mouse	SCD1-14721M	Recombinant Mouse SCD1 Protein	Mammalian Cell	His		Inquiry
Mouse	Scd1-111M	Recombinant Mouse Scd1 Full Length Transmembrane protein, His-tagged	In vitro E. coli expression system	His	1-355aa	Inquiry
Mouse	SCD1-7927M	Recombinant Mouse SCD1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Scd1-3861M	Recombinant Mouse Scd1 protein, His&Myc-tagged	E.coli	His&Myc	260-355aa	Inquiry
Mouse	SCD1-7927M-B	Recombinant Mouse SCD1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	SCD1-5247R	Recombinant Rat SCD1 Protein	Mammalian Cell	His		Inquiry
Rat	SCD1-4906R	Recombinant Rat SCD1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SCD1-4906R-B	Recombinant Rat SCD1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mus musculus (Mouse)	RFL13793MF	Recombinant Full Length Mouse Acyl-Coa Desaturase 1(Scd1) Protein, His-Tagged	E.coli expression system	His	Full Length (1-355aa)	Inquiry
Rattus norvegicus (Rat)	RFL22315RF	Recombinant Full Length Rat Acyl-Coa Desaturase 1(Scd1) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (2-358)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
SCD1 Related Articles

SCD1 involved in several pathways and played different roles in them. We selected most pathways SCD1 participated on our site, such as Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Biosynthesis of unsaturated fatty acids	ACOT2;HADHA;ELOVL6;SCD5;ELOVL2;SCD;TECR;PECR;Scd2
Fatty acid metabolism	HADHB;FADS1;ACADVL;HADHAA;ACSL1A;SCD;ACADS;ACSL4;SCD5
PPAR signaling pathway	PCK1;ILK;ACSL3A;OLR1;ADIPOQ;AQP7;ACSL4B;CYP4A10;FABP3
AMPK signaling pathway	GYS1;PIK3R5;INSR;FASN;CREB5;RAB8A;PFKFB1;EIF4EBP1;PPP2R5C

SCD1 has several biochemical functions, for example, iron ion binding, metal ion binding, oxidoreductase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCD1 itself. We selected most functions SCD1 had, and list some proteins which have the same functions with SCD1. You can find most of the proteins on our site.

Function	Related Protein
iron ion binding	CYP2AA1;CYP2P6;TPH1B;CYP4F22;ALOX15B;TPH1;CYP2C37;ACO2;P4HA1A
metal ion binding	ZFP473;Car8;ASNA1;CLCNKB;THAP10;NR6A1B;BSN;PLA2G3;ZC3H18
oxidoreductase activity	CYP2AA7;FAXDC2;H2-KE6;CYP2AA8;CYP1A1;Akr1b3;CYP2J5;HSD3B6;CYP2C37
oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	SCDB;Scd1;Scd2
palmitoyl-CoA 9-desaturase activity	Scd1;Scd2
stearoyl-CoA 9-desaturase activity	Scd2;SCD;FADS2;SCD5;Scd1

SCD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SCD1.

Samuel, W; Kutty, RK; et al. Fenretinide Induces Ubiquitin-Dependent Proteasomal Degradation of Stearoyl-CoA Desaturase in Human Retinal Pigment Epithelial Cells. JOURNAL OF CELLULAR PHYSIOLOGY 229:1028-1038(2014).

Ben-David, U; Gan, QF; et al. Selective Elimination of Human Pluripotent Stem Cells by an Oleate Synthesis Inhibitor Discovered in a High-Throughput Screen. CELL STEM CELL 12:167-179(2013).