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SCNN1G

  • Official Full Name

    sodium channel, non-voltage-gated 1, gamma subunit

  • Overview

    Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the gamma subunit, and mutations in this gene have been associated with Liddle syndrome. [provided by RefSeq, Apr 2009]
  • Synonyms

    SCNN1G; sodium channel, non-voltage-gated 1, gamma subunit; PHA1; BESC3; ENaCg; SCNEG; ENaCgamma; amiloride-sensitive sodium channel subunit gamma; gamma-ENaC; gamma-NaCH; ENaC gamma subunit; epithelial Na(+) channel subunit gamma; sodium channel, nonvoltage-gated 1, gamma; nonvoltage-gated sodium channel 1 subunit gamma; amiloride-sensitive sodium channel gamma-subunit; amiloride-sensitive epithelial sodium channel gamma subunit;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • E.Coli or Yeast
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SCNN1G-2539H Recombinant Human SCNN1G protein, His-tagged E.coli His Thr80~Thr401
Human SCNN1G-3417H Recombinant Human SCNN1G, His-tagged E.Coli or Yeast His 649
Human SCNN1G-1570HCL Recombinant Human SCNN1G cell lysate N/A
Human SCNN1G-300H Recombinant Human SCNN1G protein, His-tagged E. coli His Met1~Val182
Mouse SCNN1G-14768M Recombinant Mouse SCNN1G Protein Mammalian Cell His
Mouse SCNN1G-7940M Recombinant Mouse SCNN1G Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SCNN1G-7940M-B Recombinant Mouse SCNN1G Protein Pre-coupled Magnetic Beads HEK293
Rat Scnn1g-3418R Recombinant Rat Scnn1g, His-tagged E.Coli or Yeast His 650
Rat SCNN1G-5273R Recombinant Rat SCNN1G Protein Mammalian Cell His
Rat SCNN1G-4932R Recombinant Rat SCNN1G Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SCNN1G-4932R-B Recombinant Rat SCNN1G Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SCNN1G Related Articles

SCNN1G involved in several pathways and played different roles in them. We selected most pathways SCNN1G participated on our site, such as Taste transduction, Aldosterone-regulated sodium reabsorption, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCNN1G were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Taste transductionPRKACG;TAS2R108;SCNN1B;TAS2R117;TAS2R137;TAS2R3;TAS2R125;PRKACB;TAS2R124
Aldosterone-regulated sodium reabsorptionPIK3CD;PIK3CA;IGF1;INS2;INS;NR3C2;FXYD4;INS1;FXYD2

SCNN1G has several biochemical functions, for example, WW domain binding, ion channel activity, contributes_to ligand-gated sodium channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCNN1G itself. We selected most functions SCNN1G had, and list some proteins which have the same functions with SCNN1G. You can find most of the proteins on our site.

Function Related Protein
WW domain bindingTMEM128;LITAF;NFE2;WBP1;CDC25C;TRAF4;TCEAL5;DNM2;SHISA5
ion channel activitySCNN1G;KCNC1B;GRIA4B;CHRNA2A;CLCN4-2;CACNA1DA;TRPC4A;CNGA4;P2RX4A
contributes_to ligand-gated sodium channel activitySCNN1A;SCNN1G;SCNN1B
protein bindingSGTA;TRAF4;ZNF10;RBM11;MED30;SDHAF2;TTLL6;ATP6V0A4;MAPKAP1
sodium channel activityPKD2L1;SCN8AA;ACCN5;SCN12AB;ASIC4B;SCN8AB;ASIC4;ASIC1B;SCN11A

SCNN1G has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCNN1G here. Most of them are supplied by our site. Hope this information will be useful for your research of SCNN1G.

COMMD1; NEDD4

Yang, KQ; Lu, CX; et al. A novel frameshift mutation of epithelial sodium channel beta-subunit leads to Liddle syndrome in an isolated case. CLINICAL ENDOCRINOLOGY 82:611-614(2015).
Yang, XL; He, J; et al. Associations of Epithelial Sodium Channel Genes With Blood Pressure Changes and Hypertension Incidence: The GenSalt Study. AMERICAN JOURNAL OF HYPERTENSION 27:1370-1376(2014).
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