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SEC13

  • Official Full Name

    SEC13 homolog (S. cerevisiae)

  • Overview

    The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found.
  • Synonyms

    SEC13; SEC13 homolog (S. cerevisiae); D3S1231E, SEC13 (S. cerevisiae) like 1 , SEC13 like 1 (S. cerevisiae) , SEC13L1; protein SEC13 homolog; npp 20; SEC13R; D3S1231E; Npp20; SEC13 (S. cerevisiae) like 1; SEC13 homolog; SEC13 like 1 (S. cerevisiae); SEC13 like 1 isoform; SEC13 like protein 1; SEC13 protein; SEC13 related protein; SEC13-like protein 1; SEC13-related protein; SEC13_HUMAN; SEC13L1; SEC13-like 1 isoform; npp-20;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SEC13-3505H Recombinant Human S100 Aalcium Binding Protein A16, His-tagged E.coli His
Human SEC13-2000HCL Recombinant Human SEC13 293 Cell Lysate HEK293 N/A
Human SEC13-3774H Recombinant Human SEC13 protein, GST-tagged E.coli GST 1-325 aa
Mouse SEC13-14819M Recombinant Mouse SEC13 Protein Mammalian Cell His
Mouse Sec13-468M Recombinant Mouse Sec13 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse SEC13-7982M Recombinant Mouse SEC13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SEC13-7982M-B Recombinant Mouse SEC13 Protein Pre-coupled Magnetic Beads HEK293
Rat SEC13-5298R Recombinant Rat SEC13 Protein Mammalian Cell His
Rat SEC13-4957R Recombinant Rat SEC13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SEC13-4957R-B Recombinant Rat SEC13 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SEC13-4120R Recombinant Rhesus monkey SEC13 Protein, His-tagged Mammalian Cell His
Rhesus Macaque SEC13-3937R-B Recombinant Rhesus Macaque SEC13 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SEC13-3937R Recombinant Rhesus Macaque SEC13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish SEC13-12520Z Recombinant Zebrafish SEC13 Mammalian Cell His
Chicken SEC13-5193C Recombinant Chicken SEC13 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SEC13 Related Articles

SEC13 involved in several pathways and played different roles in them. We selected most pathways SEC13 participated on our site, such as RNA transport, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportSMN2;FMR1;POP7;GEMIN2;ELAC1;POP1;EIF4E2RS1;POP5;XPOT
Protein processing in endoplasmic reticulumTRAF2;HSPA5;GANAB;PPP1R15A;FBXO6;HSP90AA1;SYVN1;PDIA3;SEC24D

SEC13 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC13 itself. We selected most functions SEC13 had, and list some proteins which have the same functions with SEC13. You can find most of the proteins on our site.

Function Related Protein
protein bindingSEC13;CXADR;MTIF3;PDZK1;FEM1B;CD300LG;RHEB;RNF2;SLC11A2

SEC13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC13 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC13.

NUP145; TRAF5; Nup98; Nup107; SEC16B

Siddiqi, S; Mansbach, CM; et al. Phosphorylation of Sar1b Protein Releases Liver Fatty Acid-binding Protein from Multiprotein Complex in Intestinal Cytosol Enabling It to Bind to Endoplasmic Reticulum (ER) and Bud the Pre-chylomicron Transport Vesicle. JOURNAL OF BIOLOGICAL CHEMISTRY 287:10178-10188(2012).
Sihn, CR; Suh, EJ; et al. Sec13 induces genomic instability in U2OS cells. EXPERIMENTAL AND MOLECULAR MEDICINE 37:255-260(2005).
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