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SHC2

  • Official Full Name

    SHC (Src homology 2 domain containing) transforming protein 2

  • Overview

    SHC-transforming protein 2 is a protein that in humans is encoded by the SHC2 gene, SHC2 has been shown to interact with Kinase insert domain receptor.
  • Synonyms

    SHC2; SHC (Src homology 2 domain containing) transforming protein 2; SHC-transforming protein 2; neuronal Shc adaptor homolog; SCK; SHCB; SLI; Protein Sck; SH2 domain protein C2; SHC transforming protein 2; Src homology 2 domain containing transforming protein C2; SHC-transforming protein B; src homology 2 domain-containing-transforming protein C2;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse SHC2-15091M Recombinant Mouse SHC2 Protein Mammalian Cell His
Mouse Shc2-1745M Recombinant Mouse Shc2 protein, His & T7-tagged E.coli His/T7 Asp98~Glu302 (Accession # Q8BMC3)
Mouse SHC2-8142M-B Recombinant Mouse SHC2 Protein Pre-coupled Magnetic Beads HEK293
Mouse SHC2-8142M Recombinant Mouse SHC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SHC2-5390R Recombinant Rat SHC2 Protein Mammalian Cell His
Rat SHC2-5049R Recombinant Rat SHC2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SHC2-5049R-B Recombinant Rat SHC2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SHC2-4062Z Recombinant Zebrafish SHC2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SHC2 Related Signal Pathway

SHC2 involved in several pathways and played different roles in them. We selected most pathways SHC2 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ErbB signaling pathwayRPS6KB1;PAK7;PRKCG;ERBB4;MAPK8A;STAT5B;EREG;CDKN1BB;AREGB
Ras signaling pathwayRASAL2;RAB5B;RASGRP3;IKBKB;GNG13;FOXO4;PIK3CA;FASLG;GNG8
Chemokine signaling pathwayCXCL9;GNG3;GRK6;ROCK1;GSK3B;Adcy4;MAP2K1;CXCL2;GM13304
Phospholipase D signaling pathwayGRB2;GNA12;INS;HRAS;TSC1;MAPK1;PTGFR;PIK3R2;SHC1
VEGF signaling pathwayRAC1B;PLCG1;RAC3;MAPKAPK2A;RAC1A;PXNA;SPHK2;MAPK12A;PPP3R1B
Focal adhesionRAP1AA;ITGA1;MAPK10;COL11A1A;COMP;PPP1R12C;MYL12.2;RHOAD;VCLA
Natural killer cell mediated cytotoxicityVAV3;SHC1;GZMB;IFNB1;SOS1;RAET1E;IFNA10;SAMD3;NCR2
Neurotrophin signaling pathwayIKBKB;PSEN2;AKT1;RAC1;MAPK9;RPS6KA3;SH2B3;RAF1;PIK3CA
Insulin signaling pathwayCALM3;PRKAB1;RHOQ;IRS4;PRKAG1;PTPN1;HK2;HKDC1;FLOT1
Estrogen signaling pathwayGABBR2;AKT2;GNAI1;CREB5;SHC3;PLCB1;CALM4;PLCB3;GNAI2
Prolactin signaling pathwaySOCS2;PIK3CD;SOCS5;FOS;SOS1;NEK3;CSN2;MAPK11;CSH
AlcoholismHDAC8;HDAC2;HIST2H3C2;HDAC4;MAP2K1;SLC18A2;HIST1H2AM;GNG2;HIST1H2BK
Bacterial invasion of epithelial cellsSEPT11;ILK;RAC1;ARPC3;RHOA;WASL;WASF1;SHC2;CBL
GliomaPIK3CD;PRKCG;CCND1;TP53;IGF1R;CAMK2D;KRAS;AKT1;SHC2
Chronic myeloid leukemiaRAF1;BCL2L1;ABL1;CTBP2;MAPK3;PIK3CB;TGFB2;PIK3R2;SHC3

SHC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SHC2 itself. We selected most functions SHC2 had, and list some proteins which have the same functions with SHC2. You can find most of the proteins on our site.

Function Related Protein

SHC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC2.

ABI1

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