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SNAPIN

  • Official Full Name

    SNAP-associated protein

  • Overview

    The protein encoded by this gene is a coiled-coil-forming protein that associates with the SNARE (soluble;N-ethylmaleimide-sensitive fusion protein attachment protein receptor) complex of proteins and the BLOC-1 (biogenesis;of lysosome-related organelles) complex. Biochemical studies have identified additional binding partners. As part of;the SNARE complex, it is required for vesicle docking and fusion and regulates neurotransmitter release. The BLOC-1;complex is required for the biogenesis of specialized organelles such as melanosomes and platelet dense granules.;Mutations in gene products that form the BLOC-1 complex have been identified in mouse strains that are models of;Hermansky-Pudlak syndrome. Alternative splicing results in multiple transcript variants.
  • Synonyms

    SNAPIN; SNAP-associated protein; SNAPAP; SNARE-associated protein Snapin; SNAP 25 binding protein; SNAP-25-binding protein; SNARE associated protein snapin; synaptosomal-associated protein 25-binding protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SNAPIN-307H Recombinant Human SNAP-associated Protein E.coli His
Human SNAPIN-30508TH Recombinant Human SNAPIN, His-tagged E.coli His
Human SNAPIN-30509TH Recombinant Human SNAPIN, His-tagged E.coli His
Human SNAPIN-2836H Recombinant Human SNAPIN, His-tagged E.coli His 0-136AA
Human SNAPIN-1635HCL Recombinant Human SNAPIN 293 Cell Lysate HEK293 N/A
Human SNAPAP-691H Recombinant Human SNAPAP Protein, His-tagged E.coli His Ala2~Lys136
Human SNAPIN-3210H Recombinant Human SNAPIN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SNAPIN-2091HFL Recombinant Full Length Human SNAPIN Protein, C-Flag-tagged Mammalian cells Flag
Human SNAPIN-2054H Recombinant Human SNAPIN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SNAPIN-2054H-B Recombinant Human SNAPIN Protein Pre-coupled Magnetic Beads HEK293
Mouse SNAPIN-15672M Recombinant Mouse SNAPIN Protein Mammalian Cell His
Mouse Snapin-5995M Recombinant Mouse Snapin Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SNAPIN-8523M Recombinant Mouse SNAPIN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SNAPIN-8523M-B Recombinant Mouse SNAPIN Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SNAPIN-4365R Recombinant Rhesus monkey SNAPIN Protein, His-tagged Mammalian Cell His
Rhesus Macaque SNAPIN-4181R Recombinant Rhesus Macaque SNAPIN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SNAPIN-4181R-B Recombinant Rhesus Macaque SNAPIN Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SNAPIN-4181Z Recombinant Zebrafish SNAPIN Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SNAPIN Related Research Area

SNAPIN involved in several pathways and played different roles in them. We selected most pathways SNAPIN participated on our site, such as Clathrin derived vesicle budding, Golgi Associated Vesicle Biogenesis, Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with SNAPIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Clathrin derived vesicle buddingTPD52L1;TGOLN2;AP4B1;TFR1B;AP1G1;PICALMB;PPIAL4A;AP1M2;HIP1R
Golgi Associated Vesicle BiogenesisYIPF6;GAK;CPD;PICALMB;AP1M2;AP3S1;NAPAA;PUM1;SH3D19
Membrane TraffickingBLOC1S6;BLOC1S1;STXBP3;PICALMB;TRAPPC6B;TRAPPC9;EXOC3;FTH1A;COPG
Vesicle-mediated transportGJB4;TRAPPC10;AP1S3A;CD163;STXBP3;SNX9;PPP6R1;RAB10;DNASE2
trans-Golgi Network Vesicle BuddingAP4B1;PICALMA;CNO;NECAP1;BLOC1S6;GAK;FTH1A;SH3D19;CLVS1

SNAPIN has several biochemical functions, for example, SNARE binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SNAPIN itself. We selected most functions SNAPIN had, and list some proteins which have the same functions with SNAPIN. You can find most of the proteins on our site.

Function Related Protein
SNARE bindingSTX4;SYBL1;STX1A;STX1B;STXBP1;VTI1A;SNAPIN;STX4A;MYO5A
protein bindingSMAD5;SOSTDC1B;ASCC3;ACAA2;RBM10;TTC25;PROP1;MKI67IP;LACE1

SNAPIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SNAPIN here. Most of them are supplied by our site. Hope this information will be useful for your research of SNAPIN.

BLOC1S2; DTNBP1; LRRK2; Slc14a2

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