spna2
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  • Official Full Name
  • spectrin alpha 2
  • Synonyms
  • SPNA2;spectrin alpha 2;ENSMUSG00000057738;Spna-2;Sptan1;2610027H02Rik;2 B;2 18.0 cM;spectrin alpha chain, brain;spectrin alpha chain, brain;alpha-fodrin;alpha-II spectrin;fodrin alpha chain;alpha-spectrin 2, brain;spectrin, non-erythroid alpha chain;
Cat.#:SPNA2-5689ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SPNA2
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Involved Pathway

Spna2 involved in several pathways and played different roles in them. We selected most pathways Spna2 participated on our site, such as ARMS-mediated activation, Apoptosis, Apoptotic cleavage of cellular proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with Spna2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
ARMS-mediated activation
SPNA2; DLG4; PSMD5; NETO2; HBEGF; DUSP6; DUSP10; NRG4; DUSP5; WDR83
Apoptosis
IRAK3; Gzmg; RELA; AKT1; CASP3B; DSP; PPP3CA; ADD1; CASP8; DBNLB
Apoptotic cleavage of cellular proteins
DSP; SATB1; CTNNB1; PLEC; GAS2; OCLN; BMX; DBNL; DSG1; SPNA2
Apoptotic execution phase
CTNNB2; CASP6L1; HMGB2; BMX; DFFA; LMNB1; PANK1A; DBNLA; STK26; HIST1H1C
Axon guidance
UNC5C; PLXNC1; SEMA4D; EFNA5; DPYSL5B; PTK2; CNKSR1; GSK3B; ROBO1; NTN1A
Caspase-mediated cleavage of cytoskeletal proteins
ADD1; CASP6L2; DBNLB; SPNA2; PLEC; GAS2; VIML; DBNLA; DBNL; PLECA
Cytokine Signaling in Immune system
RASGEF1A; TNFRSF13C; XAF1; LGALS9; MAP3K8; SPRED3; TRIM2; TRIM31; IRF2; CNKSR1
DAP12 interactions
LAMTOR2; PAQR3A; KIR2DS2; THEM4; NRG3; SPRED2; DUSP7; SIGLEC14; SPTB; SPRED3

Protein Function

Spna2 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Spna2 itself. We selected most functions Spna2 had, and list some proteins which have the same functions with Spna2. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein THBS4; SLC25A25B; PCDH2AB6; PSPH; GSN; MBL1; MGP; AASS; GPD2; MYL6

Interacting Protein

Spna2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Spna2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Spna2.
piwil2

Spna2 Related Articles

Chin, MS; Hooper, LC; et al. Identification of alpha-fodrin as an autoantigen in experimental coronavirus retinopathy (ECOR). JOURNAL OF NEUROIMMUNOLOGY 272:42-50(2014).
Valiyaveettil, M; Alamneh, YA; et al. Cytoskeletal protein alpha-II spectrin degradation in the brain of repeated blast exposed mice. BRAIN RESEARCH 1549:32-41(2014).