sprtn
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  • Official Full Name
  • SprT-like N-terminal domain
  • Synonyms
Cat.#:SPRTN-1356HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human SPRTN
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Cat.#:SPRTN-15942MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SPRTN Protein
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Cat.#:SPRTN-222HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SPRTN cell lysate
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Involved Pathway

Sprtn involved in several pathways and played different roles in them. We selected most pathways Sprtn participated on our site, such as DNA Damage Bypass, DNA Repair, Translesion Synthesis by POLH, which may be useful for your reference. Also, other proteins which involved in the same pathway with Sprtn were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA Damage Bypass
SPRTN; POLI; ZBTB32; DDB1; POLD3; DTL; USP10; KIAA0101; MAD2L2; USP43A
DNA Repair
WRN; DDB1; RAD9A; RTEL1; RNF111; CHD1L; ASCC3; RAD1; UBE2L6; YY1A
Translesion Synthesis by POLH
SPRTN
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
KIAA0101; USP10; USP43; SPRTN; POLI; USP43A

Protein Function

Sprtn has several biochemical functions, for example, DNA binding, K63-linked polyubiquitin binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Sprtn itself. We selected most functions Sprtn had, and list some proteins which have the same functions with Sprtn. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein SOX1B; ZNF563; ZNF597; ZBED1; PARP2; MBD1B; ADNP; ELF2A; NR4A3; ZNF136
Function K63-linked polyubiquitin binding
Related Protein OTUD7B; SQSTM1; TAB2; SPRTN; ZRANB1; UIMC1; TNFAIP3; ZRANB3; RNF169; ATRIP
Function metal ion binding
Related Protein PON2; MICALL2B; ZNF558; JAZF1B; DNAJA4; PVALB5; Adamts19; CRBN; FBP2; MCM10
Function protein binding
Related Protein ITCH; UBB; WLS; PRRG2; PTK2B; TRADD; TREML2; TMEM115; MAP6; C10orf119
Function ubiquitin binding
Related Protein TSG101; SIRT2; UBE2N; KIF18A; BRAP; SPRTN; RNF168; UBR5; PER2; HSPB1

Interacting Protein

Sprtn has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Sprtn here. Most of them are supplied by our site. Hope this information will be useful for your research of Sprtn.
RALGAPA2; EMC2; BRAP; BCL7C