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STIM2

  • Official Full Name

    stromal interaction molecule 2

  • Overview

    Ca2+ is a key second messenger in many intracellular signaling pathways. Ca2+ signals control many cellular functions ranging from short-term responses such as contraction and secretion to longer-term regulation of cell growth and proliferation. Stromal i
  • Synonyms

    STIM2; stromal interaction molecule 2; FLJ39527; KIAA1482;

  • Recombinant Proteins
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • GST
  • His
  • Myc
  • DDK
  • MYC
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human STIM2-3005H Recombinant Human STIM2, GST-tagged E.coli GST 446-595aa
Human STIM2-4194H Recombinant Human STIM2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human STIM2-2885H Recombinant Human STIM2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human STIM2-005H Recombinant Human STIM2 Protien, His-tagged E. coli His 525-674 aa
Mouse Stim2-582M Recombinant Mouse Stim2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mus musculus (Mouse) RFL3056MF Recombinant Full Length Mouse Stromal Interaction Molecule 2(Stim2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (15-746)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • STIM2 Related Articles

STIM2 involved in several pathways and played different roles in them. We selected most pathways STIM2 participated on our site, such as Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with STIM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayORAI2;TRHR;LHCGR;DRD1A;CAMK2G;PRKACAB;PTK2B;SLC8A1;PDGFRA

STIM2 has several biochemical functions, for example, calcium channel regulator activity, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by STIM2 itself. We selected most functions STIM2 had, and list some proteins which have the same functions with STIM2. You can find most of the proteins on our site.

Function Related Protein
calcium channel regulator activityGRM2;STIM1A;CRISP1;CAV3;PRKCB;TSPAN13;TSPAN13B;SGK2A;CACNA2D1
calcium ion bindingATP2A1;ABP1;GSN;SULF2B;PCDH1;PCDH1G22;ADAMTS13;KCNIP1B;CALB2B
protein bindingUFL1;FBXO7;NCALD;TMEM74;ATP6V1C2;TGM2;CRH;C1orf65;CIDEB
store-operated calcium channel activityTRPC2B;TRPC6A;ORAI2;ORAI3;TRPC3;STIM2;TRPC6;TRPC1;TRPC2

STIM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with STIM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of STIM2.

CALM; PRKAB2; PRKAA2; STIM1; PRPF40A

Matsumoto, M; Baba, Y; et al. Role of STIM-dependent Ca2+ Influx in Regulatory B Cells. YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN 133:419-425(2013).
Matsumoto, M; Fujii, Y; et al. The Calcium Sensors STIM1 and STIM2 Control B Cell Regulatory Function through Interleukin-10 Production. IMMUNITY 34:703-714(2011).
Thiel, M; Wolfs, MJ; et al. Efficiency of T-cell costimulation by CD80 and CD86 cross-linking correlates with calcium entry. IMMUNOLOGY 129:28-40(2010).
Skibinska-Kijek, A; Wisniewska, MB; et al. Immunolocalization of STIM1 in the mouse brain. ACTA NEUROBIOLOGIAE EXPERIMENTALIS 69:413-428(2009).
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