TACR1
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Official Full Name
TACR1 tachykinin receptor 1
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Overview
This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. -
Synonyms
TACR1; tachykinin receptor 1; TAC1R; substance-P receptor; NK1R; NKIR; SPR; NK-1R; NK-1 receptor; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor);
- Cell & Tissue Lysates
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Canis lupus familiaris (Dog) (Canis familiaris)
- Cavia porcellus (Guinea pig)
- Chicken
- Human
- Lithobates catesbeiana (American bullfrog) (Rana catesbeiana)
- Meriones unguiculatus (Mongolian jird) (Mongolian gerbil)
- Mouse
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- E.coli
- E.coli expression system
- HEK293
- Insect Cell
- Mammalian Cell
- Flag
- 10His
- GST
- His
- His (Fc)
- Avi
- N/A
- N
- C
- 10×His
- Involved Pathway
- Protein Function
- Interacting Protein
- TACR1 Related Research Area
TACR1 involved in several pathways and played different roles in them. We selected most pathways TACR1 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, Measles, which may be useful for your reference. Also, other proteins which involved in the same pathway with TACR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Calcium signaling pathway | HTR2CL1;PHKG2;GNAS;STIM1A;PTK2B;PLCB2;CYSLTR2;SLC8A4A;CAMK2D |
Neuroactive ligand-receptor interaction | TAAR13D;P2RX6;GHRHRL;VIPR2;CGNRH-R;GZMA;CHRNA2A;MTNR1A;NPY7R |
Measles | NFKBIA;IFNA14;TYK2;PIK3CB;TP53;EIF2AK2;IRAK1;IFNB1;OAS1 |
TACR1 has several biochemical functions, for example, protein binding, substance P receptor activity, tachykinin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TACR1 itself. We selected most functions TACR1 had, and list some proteins which have the same functions with TACR1. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | TMEM218;CDPF1;CAND1;S1PR3;KIR2DL1;ATP1A2;MAPKAPK2;SNAP29;FCHSD2 |
substance P receptor activity | TACR1A;TACR1 |
tachykinin receptor activity | TACR3L;TACR1;TACR1B;TACR2;TACR1A;TACR3;TACR3A |
TACR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TACR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TACR1.
TAC1
- Q&As
- Reviews
Q&As (5)
Ask a questionYes, understanding individual variations in TACR1 protein may lead to personalized approaches for pain management.
Dysregulation of TACR1 protein is implicated in chronic pain conditions such as fibromyalgia, migraine, and neuropathic pain.
Yes, drugs targeting TACR1 protein, such as NK1 receptor antagonists, are being investigated for their potential in managing pain.
Yes, genetic variations in TACR1 protein have been associated with differences in pain sensitivity and susceptibility to chronic pain conditions.
Side effects of targeting TACR1 protein may include nausea, vomiting, and potential effects on mood and emotional state.
Customer Reviews (3)
Write a reviewThis level of support instills trust and confidence in the product, facilitating smooth and successful experimentation.
The TACR1 protein comes highly recommended for a variety of research applications.
Its exceptional performance in ELISA assays makes it a reliable tool for detecting and quantifying specific target molecules with high sensitivity and specificity.
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