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TACR2

  • Official Full Name

    tachykinin receptor 2

  • Overview

    This gene belongs to a family of genes that function as receptors for tachykinins. Receptor affinities are specified by variations in the 5'-end of the sequence. The receptors belonging to this family are characterized by interactions with G proteins and 7 hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin neuropeptide substance K, also referred to as neurokinin A.
  • Synonyms

    TACR2; tachykinin receptor 2; NKNAR, TAC2R; substance-K receptor; NK2R; SKR; NK-2R; NK-2 receptor; substance K receptor; neurokinin 2 receptor; neurokinin A receptor; seven transmembrane helix receptor; NKNAR; TAC2R;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Canis lupus familiaris (Dog) (Canis familiaris)
  • Cavia porcellus (Guinea pig)
  • Homo sapiens (Human)
  • Human
  • Mesocricetus auratus (Golden hamster)
  • Mouse
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TACR2-613H Recombinant Human TACR2 protein, His-tagged E.coli His Val92~Leu290 (Accession # P21452)
Human TACR2-1282HCL Recombinant Human TACR2 293 Cell Lysate HEK293 N/A
Mouse TACR2-16377M Recombinant Mouse TACR2 Protein Mammalian Cell His
Mouse TACR2-8958M Recombinant Mouse TACR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse TACR2-8958M-B Recombinant Mouse TACR2 Protein Pre-coupled Magnetic Beads HEK293
Rat TACR2-5907R Recombinant Rat TACR2 Protein Mammalian Cell His
Rat Tacr2-614R Recombinant Rat Tacr2 protein, His & T7-tagged E.coli His/T7 Met1~Val200 (Accession # P16610)
Rat TACR2-5566R-B Recombinant Rat TACR2 Protein Pre-coupled Magnetic Beads HEK293
Rat TACR2-5566R Recombinant Rat TACR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL9652BF Recombinant Full Length Bovine Substance-K Receptor(Tacr2) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Canis lupus familiaris (Dog) (Canis familiaris) RFL26532CF Recombinant Full Length Dog Substance-K Receptor(Tacr2) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Cavia porcellus (Guinea pig) RFL7357CF Recombinant Full Length Guinea Pig Substance-K Receptor(Tacr2) Protein, His-Tagged E.coli expression system His Full Length (1-402)
Homo sapiens (Human) RFL389HF Recombinant Full Length Human Substance-K Receptor(Tacr2) Protein, His-Tagged E.coli expression system His Full Length (1-398)
Mesocricetus auratus (Golden hamster) RFL7030MF Recombinant Full Length Mesocricetus Auratus Substance-K Receptor(Tacr2) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Mus musculus (Mouse) RFL4631MF Recombinant Full Length Mouse Substance-K Receptor(Tacr2) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Oryctolagus cuniculus (Rabbit) RFL29481OF Recombinant Full Length Rabbit Substance-K Receptor(Tacr2) Protein, His-Tagged E.coli expression system His Full Length (1-384)
Rattus norvegicus (Rat) RFL16149RF Recombinant Full Length Rat Substance-K Receptor(Tacr2) Protein, His-Tagged E.coli expression system His Full Length (1-390)
Kit-0902 CYP2D6 Cyan Screening Kit N/A
Kit-1532 TACR2 CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1533 TACR2 Activated GPCR Internalization Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TACR2 Related Articles
  • TACR2 Related Research Area

TACR2 involved in several pathways and played different roles in them. We selected most pathways TACR2 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with TACR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayRYR2;SPHK2;CALM;AGTR1B;PLCD3;CACNA1H;P2RX3A;ADRB3A;GRIN1A
Neuroactive ligand-receptor interactionTAAR12C;TAAR14E;GRIK5;OPRD1A;NPBWR2;NPFFR1;TAAR12I;TAAR14G;CALCR

TACR2 has several biochemical functions, for example, protein binding, substance K receptor activity, tachykinin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TACR2 itself. We selected most functions TACR2 had, and list some proteins which have the same functions with TACR2. You can find most of the proteins on our site.

Function Related Protein
protein bindingNR2F6;CLOCKB;DNAJC5B;PRLR;REV1;BCCIP;PARP9;RAB27B;CUL1
substance K receptor activity
tachykinin receptor activityTACR2;TACR1;TACR1A;TACR3;TACR3L;TACR1B;TACR3A

TACR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TACR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of TACR2.

TAC1

Takeda, M; Miyake, M; et al. Proliferation of sensory C-fibers and subsequent neurogenic inflammation in rat airway induced by inhaled lipopolysaccharide. NEUROTOXICOLOGY 32:954-962(2011).
Verhein, KC; Hazari, MS; et al. Three days after a single exposure to ozone, the mechanism of airway hyperreactivity is dependent on substance P and nerve growth factor. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY 300:L176-L184(2011).
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