taf13
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  • Official Full Name
  • TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
  • Background
  • Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6.
  • Synonyms
  • TAF13; TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa; TAF2K, TATA box binding protein (TBP) associated factor, RNA polymerase II, K, 18kD; transcription initiation factor TFIID subunit 13; TAFII18; MGC22425; TAF(II)18; TAF13 RNA polymerase II, TATA box binding protein (TBP) associated factor, 18kDa; TAF13_HUMAN; TAF2K; TAFII 18; TAFII-18; Transcription initiation factor TFIID 18 kDa subunit; OTTHUMP00000039343; OTTHUMP00000039344; transcription initiation factor TFIID 18 kD subunit; TATA box binding protein (TBP)-associated factor, RNA polymeras
Cat.#:TAF13-1226HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TAF13 protein, His & T7-tagged
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Cat.#:TAF13-1399CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TAF13
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Cat.#:TAF13-1375ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TAF13
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Cat.#:TAF13-1275HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TAF13 293 Cell Lysate
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Involved Pathway

TAF13 involved in several pathways and played different roles in them. We selected most pathways TAF13 participated on our site, such as Basal transcription factors, Herpes simplex infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Basal transcription factors
GTF2A1L; CDK7; TAF3; TBP; GTF2H5; MNAT1; TAF6; GTF2H1; GTF2A1; TAF11
Herpes simplex infection
TAF6; HLA-B; JAK2B; NXF2; HLA-DOA; IFNA8; NFKBIA; MHC1UEA; MAPK8A; OAS2

Protein Function

TAF13 has several biochemical functions, for example, DNA binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF13 itself. We selected most functions TAF13 had, and list some proteins which have the same functions with TAF13. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZFP451; TLX2; ZNF133; GTF2IRD1; PSMC3IP; HIST1H2BG; RUNX2B; KCNIP3; LIG3; SUPV3L1
Function protein C-terminus binding
Related Protein HPCAL4; BCAM; MSH2; TAF13; HESX1; SREBF2; SNF8; FBLN1; HOMER3; CEP120
Function protein binding
Related Protein URM1; VPS28; RERE; FHL3; NEBL; RAD1; MC2R; MRPL51; PPEF1; Serpina1b
Function protein heterodimerization activity
Related Protein EXT1; ITGA3; ZBTB1; CHRAC1; AGTR1; SPTAN1; MICU1; MYH7; SDCBP; DRD1
Function transcription cofactor activity
Related Protein LDB2A; ZNF763; ZNF710A; MED17; SUPT20H; ZNF212; ANKRA2; ZNF671; PHF21A; PTPN14
Function transcription factor activity, sequence-specific DNA binding
Related Protein CREB3L3A; TP73; CBFB; NKX2; TFCP2L1; FOXN2B; ZNF213; PAX3; FOXM1; KLF11

Interacting Protein

TAF13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF13 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF13.
MTUS2; TAF11; h3_peptide_2-18; MED26; CERK; NAF1; NLRP2