taf1c
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  • Official Full Name
  • TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
  • Background
  • Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding;protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds;to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory;signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding;different isoforms have been identified.
  • Synonyms
  • TAF1C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein (TBP) associated factor, RNA polymerase I, C, 110kD; TATA box-binding protein-associated factor RNA polymerase I subunit C; MGC:39976; SL1; TAFI
Cat.#:TAF1C-30935THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TAF1C, His-tagged
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Cat.#:TAF1C-16392MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TAF1C Protein
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Cat.#:TAF1C-5915RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TAF1C Protein
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Cat.#:TAF1C-1733HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human TAF1C cell lysate
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Involved Pathway

TAF1C involved in several pathways and played different roles in them. We selected most pathways TAF1C participated on our site, such as Epigenetic regulation of gene expression, Gene Expression, Negative epigenetic regulation of rRNA expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAF1C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Epigenetic regulation of gene expression
SAP30; DNMT3L; JARID2B; DNMT3A; DNMT1; SAP18; JARID2; RRP8; TAF1B; TAF1D
Gene Expression
ZNF257; ZNF184; NKX2; AIMP2; AGO3B; ESRRA; ZNF446; CDKAL1; ZNF713; TNRC6B
Negative epigenetic regulation of rRNA expression
SIN3B; SAP130; TAF1B; BAZ2A; TAF1C; CD3EAP; EFCAB11; DNMT1; RRP8; SAP30BP
NoRC negatively regulates rRNA expression
TAF1C; EFCAB11; SAP30BP; SAP130; SUDS3; DNMT1; TAF1A; CD3EAP; SIN3B; BAZ2A
RNA Polymerase I Chain Elongation
CD3EAP; TAF1C; CBX3A; EFCAB11; CBX3; UBTF; TAF1D; TAF1B; TAF1A
RNA Polymerase I Promoter Clearance
UBTF; MTA3; TAF1D; EHMT2; TAF1A; MTA1; TAF1C; RRN3; CHD4A; MBD3A
RNA Polymerase I Promoter Escape
RRN3; TAF1B; UBTF; TAF1D; EFCAB11; TAF1A; TAF1C; CD3EAP
RNA Polymerase I Transcription
CHD4; TAF1A; PTRFB; CD3EAP; GATAD2A; TAF1D; PTRF; UBTF; TAF1C; GATAD2AB

Protein Function

TAF1C has several biochemical functions, for example, RNA polymerase I CORE element sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TAF1C itself. We selected most functions TAF1C had, and list some proteins which have the same functions with TAF1C. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase I CORE element sequence-specific DNA binding
Related Protein EFCAB11; RRN3; SMARCA4; TAF1B; PIH1D1; TAF1C; BAZ2A; SMARCB1
Function protein binding
Related Protein TFR2; ADORA1; BLMH; CAND2; TOMM70A; STARD13; IK; GRAP; ADCK3; STXBP4

Interacting Protein

TAF1C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAF1C here. Most of them are supplied by our site. Hope this information will be useful for your research of TAF1C.
TBP; SET; TAF12; TAF1B; TAF1D; TTR; TK1; H2AFX; SMN1; UFD1L