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TBC1D1

Official Full Name

TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
Overview

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a;role in regulating cell growth and differentiation. These proteins share significant homology with TRE2 (USP6; MIM;604334), yeast Bub2, and CDC16 (MIM 603461) (White et al., 2000 (PubMed 10965142)).
Synonyms

TBC1D1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; TBC1 domain family member 1; KIAA1108; TBC; TBC1;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque

Source

E.coli
HEK293
HEK293T
Mammalian Cell
Mammalian cells

Tag

Flag
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TBC1D1-329H	Recombinant Human TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1, His-tagged	E.coli	His	Inquiry
Human	TBC1D1-1232HCL	Recombinant Human TBC1D1 293 Cell Lysate	HEK293	N/A	Inquiry
Human	TBC1D1-2159H-B	Recombinant Human TBC1D1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Human	TBC1D1-1632H	Recombinant Human TBC1D1 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Human	TBC1D1-1100HFL	Recombinant Full Length Human TBC1D1 Protein, C-Flag-tagged	Mammalian cells	Flag	Inquiry
Human	TBC1D1-2159H	Recombinant Human TBC1D1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	Tbc1d1-6301M	Recombinant Mouse Tbc1d1 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Rhesus Macaque	TBC1D1-4630R	Recombinant Rhesus monkey TBC1D1 Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	TBC1D1-4446R	Recombinant Rhesus Macaque TBC1D1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	TBC1D1-4446R-B	Recombinant Rhesus Macaque TBC1D1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Chicken	TBC1D1-4640C	Recombinant Chicken TBC1D1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TBC1D1 Related Articles

TBC1D1 involved in several pathways and played different roles in them. We selected most pathways TBC1D1 participated on our site, such as AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBC1D1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
AMPK signaling pathway	ADIPOQ;INS2;ULK1;CCNA2;RAB10;PFKP;PPP2R1A;G6PC3;HNF4A

TBC1D1 has several biochemical functions, for example, GTPase activator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBC1D1 itself. We selected most functions TBC1D1 had, and list some proteins which have the same functions with TBC1D1. You can find most of the proteins on our site.

Function	Related Protein
GTPase activator activity	ACAP1;RABEP2;RANGAP1A;ERRFI1;RGS21;TBC1D21;TBC1D22A;EVI5L;TBC1D1
protein binding	OPRM1;MAL;CMTM3;FAM151B;C9orf116;HJURP;NRCAM;UBR4;EIF4EBP3

TBC1D1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBC1D1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBC1D1.

YWHAG; HSPB1; SMAD2; UBE2E2; pi3p; BMH1; YWHAB; ROR1; YWHAH; GCG

Li, Z; Ni, CL; et al. Liraglutide enhances glucose transporter 4 translocation via regulation of AMP-activated protein kinase signaling pathways in mouse skeletal muscle cells. METABOLISM-CLINICAL AND EXPERIMENTAL 63:1022-1030(2014).

Ducommun, S; Wang, HY; et al. Thr(649)Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 302:E1036-E1043(2012).