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TBCC

Official Full Name

tubulin folding cofactor C
Overview

Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Synonyms

TBCC; tubulin folding cofactor C; tubulin specific chaperone c; tubulin-specific chaperone C; CFC; Beta tubulin cofactor C; tubulin-folding cofactor C;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TBCC-29834TH	Recombinant Human TBCC	Wheat Germ	N/A	346 amino acids	Inquiry
Human	TBCC-1218HCL	Recombinant Human TBCC 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TBCC-825H	Recombinant Human TBCC Protein (2-345 aa), His-tagged	E.coli	His	2-345 aa	Inquiry
Human	TBCC-518HF	Recombinant Full Length Human TBCC Protein	In Vitro Cell Free System		346 amino acids	Inquiry
Human	TBCC-3862H	Recombinant Human TBCC protein, His-tagged	E.coli	His	1-346 aa	$319 / 25ug
Mouse	TBCC-16505M	Recombinant Mouse TBCC Protein	Mammalian Cell	His		Inquiry
Mouse	TBCC-9043M	Recombinant Mouse TBCC Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Tbcc-6312M	Recombinant Mouse Tbcc Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	TBCC-9043M-B	Recombinant Mouse TBCC Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	TBCC-8142Z	Recombinant Zebrafish TBCC	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

TBCC involved in several pathways and played different roles in them. We selected most pathways TBCC participated on our site, such as Metabolism of proteins, Post-chaperonin tubulin folding pathway, Protein folding, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBCC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Metabolism of proteins	NAT8;YKT6;EIF5;ADAMTS1;ST8SIA2;ARSE;O3far1;CGB5;SEC22A
Post-chaperonin tubulin folding pathway	TBCB;TBCE;TBCC;TBCA;SERPINA7;TBCD;ARL2
Protein folding	FBXW5;ARL2;PFDN5;TBCA;TBCE;PFDN2;PFDN1;TBCC;NOP56

TBCC has several biochemical functions, for example, GTPase activity, chaperone binding, tubulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBCC itself. We selected most functions TBCC had, and list some proteins which have the same functions with TBCC. You can find most of the proteins on our site.

Function	Related Protein
GTPase activity	RASL10A;GTPBP5;RAB39A;GNAT2;RHOQ;RAP1GAP;IFT27;MXE;GNG11
chaperone binding	TIMM10;PFDN4;HSPD1;H2-KE2;PACRG;DNAJB1;HSPA5;TBCE;GET4
tubulin binding	IFT81;AGTPBP1;LRRK2;STMN4L;TPPP;RITA1;STMN1A;TBCC;FYN

TBCC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBCC here. Most of them are supplied by our site. Hope this information will be useful for your research of TBCC.