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TBCD

  • Official Full Name

    tubulin folding cofactor D

  • Overview

    Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
  • Synonyms

    TBCD; tubulin folding cofactor D; tubulin specific chaperone d; tubulin-specific chaperone D; Beta tubulin cofactor D; Beta-tubulin cofactor D; KIAA0988; SSD 1; SSD-1; SSD1; TBCD_HUMAN; tfcD; Tubulin-folding cofactor D;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TBCD-3134H Recombinant Human TBCD, His-tagged E.coli His 0-270AA
Human TBCD-1744HCL Recombinant Human TBCD cell lysate N/A
Chicken TBCD-2029C Recombinant Chicken TBCD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

TBCD involved in several pathways and played different roles in them. We selected most pathways TBCD participated on our site, such as Metabolism of proteins, Post-chaperonin tubulin folding pathway, Protein folding, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBCD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of proteinsALG10B;SERPINA7;TRAPPC5;PPP6C;SENP1;CHCHD4;PPP6R1;LMAN2;LMCD1
Post-chaperonin tubulin folding pathwayTBCC;TBCB;TBCD;TBCA;ARL2;TBCE;SERPINA7
Protein foldingKIFC3;FKBP9;PFDN6;NOP56;FBXW5;TBCE;PFDN1;PFDN4;PFDN5

TBCD has several biochemical functions, for example, GTPase activator activity, beta-tubulin binding, chaperone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBCD itself. We selected most functions TBCD had, and list some proteins which have the same functions with TBCD. You can find most of the proteins on our site.

Function Related Protein
GTPase activator activityARFGAP2;ARHGAP4A;RANGAP1A;RGS19;SRGAP2;ARHGAP35;CDC42EP3;TBC1D5;RGS14
beta-tubulin bindingSLC6A2;MAP1S;PACRG;PDCD5;SNCA;CASC1;TRPV4;VAPB;RACGAP1
chaperone bindingUBL4;HYOU1;TP53;DNAJA4;CDKN1B;DNAJA3A;DNAJB4;DLST;TBCA
protein bindingAPPL1;CACNB4;HNRNPH3;ZNF614;EPHA2;UQCC1;ALDOB;ITSN1;LGALS2

TBCD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBCD here. Most of them are supplied by our site. Hope this information will be useful for your research of TBCD.

ACD; ARL2; ARL3; Tubb4b; Tubb5; IKBKG; SMAD9; DEXI; XRCC6; POLR2I; TERF1; POT1; 1C

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