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TBL3

Official Full Name

transducin (beta)-like 3
Overview

The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This gene has multiple polyadenylation sites. It might have multiple alternatively spliced transcript variants but the variants have not been fully described yet.
Synonyms

TBL3; transducin (beta)-like 3; transducin beta-like protein 3; SAZD; UTP13; WD-repeat protein SAZD; WD repeat-containing protein SAZD;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TBL3-1211HCL	Recombinant Human TBL3 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	TBL3-16516M	Recombinant Mouse TBL3 Protein	Mammalian Cell	His	Inquiry
Mouse	TBL3-9050M	Recombinant Mouse TBL3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	TBL3-9050M-B	Recombinant Mouse TBL3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	TBL3-5971R	Recombinant Rat TBL3 Protein	Mammalian Cell	His	Inquiry
Rat	TBL3-5630R	Recombinant Rat TBL3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	TBL3-5630R-B	Recombinant Rat TBL3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	TBL3-1786Z	Recombinant Zebrafish TBL3	Mammalian Cell	His	Inquiry
Chicken	TBL3-1317C	Recombinant Chicken TBL3	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TBL3 Related Articles

TBL3 involved in several pathways and played different roles in them. We selected most pathways TBL3 participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with TBL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome biogenesis in eukaryotes	TCOF1;NXF2;DKC1;RAN;REX1;XRN2;EIF6;RRP7A;POP1

TBL3 has several biochemical functions, for example, poly(A) RNA binding, protein binding, snoRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TBL3 itself. We selected most functions TBL3 had, and list some proteins which have the same functions with TBL3. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	RPS4Y2;PA2G4;SF1;MRPS7;CANX;RTF1;GLTSCR2;ZNF622;MSI2
protein binding	POLR2C;HDAC3;TFIP11;NGLY1;LIMK2;E2F4;ZNF10;SP2;DRD1A
snoRNA binding	NUDT7;NUDT4;NUDT5;NUDT16L1;NUDT16;UTP6;UTP15;PWP2;NOP56

TBL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TBL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of TBL3.

APPBP2; DHX30; NR2E3; RBBP7; USP36; NUDC; CACNB4; SFN; USP11; AURKB; URM1

Li, JW; Wang, J; et al. Both corepressor proteins SMRT and N-CoR exist in large protein complexes containing HDAC3. EMBO JOURNAL 19:4342-4350(2000).

Huang, LQ; Shanker, YG; et al. G gamma 13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. NATURE NEUROSCIENCE 2:1055-1062(1999).