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TDG

Official Full Name

thymine-DNA glycosylase
Synonyms

TDG;thymine-DNA glycosylase;G/T mismatch-specific thymine DNA glycosylase;EC 3.2.2.29;003211;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
M. Thermoautotrophicus
Mouse

Source

E.coli
HEK293
Insect Cells
Mammalian Cell

Tag

Flag
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TDG-7443H	Human TDG protein		N/A		Inquiry
Human	TDG-7134H	Recombinant Human Thymine-DNA Glycosylase, His-tagged	E.coli	His	1-410aa	Inquiry
Human	TDG-533H	Recombinant Human TDG	Mammalian Cell	His		Inquiry
Human	TDG-1157HCL	Recombinant Human TDG 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TDG-122H	Recombinant Human TDG Protein, His-tagged	E.coli	His		Inquiry
Human	TDG-4169H-B	Recombinant Human TDG Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Human	TDG-4169H	Recombinant Human TDG Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	TDG-338M	Recombinant Mouse TDG Protein, His-tagged	Insect Cells	Flag		Inquiry
M. Thermoautotrophicus	TDG-01M	Recombinant M. Thermoautotrophicus TDG Protein	E.coli	N/A		Inquiry
Chicken	TDG-6315C	Recombinant Chicken TDG	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
TDG Related Articles

TDG involved in several pathways and played different roles in them. We selected most pathways TDG participated on our site, such as Base excision repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with TDG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Base excision repair	nth;POLD1;APEX1;mutY;xthA;NEIL1;OGG1;MUTYH;HMGB1B

TDG has several biochemical functions, for example, DNA N-glycosylase activity, RNA polymerase II transcription cofactor activity, SUMO binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TDG itself. We selected most functions TDG had, and list some proteins which have the same functions with TDG. You can find most of the proteins on our site.

Function	Related Protein
DNA N-glycosylase activity	NEIL1;OGG1;NTHL1;TDG;SMUG1;NEIL3
RNA polymerase II transcription cofactor activity	THRAP3;MED4;MED21;NKX2-5;MED15;MED19B;CNOT2;MED8;MED1
SUMO binding	USPL1;HERC2;CBX4;RPS3;USP25;PML;TOLLIP;TDG
damaged DNA binding	RAD52;RAD23A;HMGB2;EP300;ERCC3;NEIL2;POLH;UNG;RBBP8
double-stranded DNA binding	ZNF638;FEN1;KLF6;TDG;RAD51AP1;HMGB3;XRCC3;TRP63;RAD51D
mismatched DNA binding	TDG;PMS1;MLH3;MSH6;MSH5;MLH1;MSH4
protein binding	DTX1;TMEM31;PTPN6;MYOD1;PPP3CA;CIDEB;LRRC6;FBXO4;ARFGAP1
protein homodimerization activity	PRDM6;SERPINF2;PVRL1B;SYT16;TP53I3;APOA1BP;TNNC1;CADM3;BCL11A
protein kinase C binding	NELL2;PAWR;AVPR1A;SQSTM1;HSPB1;DACT2;PLEK;GRK5;LDB3
pyrimidine-specific mismatch base pair DNA N-glycosylase activity	TDG.1;TDG;MBD4
structure-specific DNA binding	TDG;SETMAR;EXO1;TET1;ENDOV
uracil DNA N-glycosylase activity	TDG;TDG.1;APEX1;UNG;UNGA;SMUG1;CCNO

TDG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TDG here. Most of them are supplied by our site. Hope this information will be useful for your research of TDG.

AICDA; GADD45A; JUNB; SKIL; STAT3; CRK; SUMO1; IKZF1; SMAD4; DDX39B; SETX; SNIP1

Thwe-Thwe-Win; Hirao, T; et al. Current genetic structure of teak (Tectona qrandis) in Myanmar based on newly developed chloroplast single nucleotide polymorphism and nuclear single sequence repeat markers. TROPICAL CONSERVATION SCIENCE 8:235-256(2015).

McLeod, HC; Roy, JW; et al. Patterns of Entrapped Air Dissolution in a Two-Dimensional Pilot-Scale Synthetic Aquifer. GROUNDWATER 53:271-281(2015).