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TFB2M

Official Full Name

transcription factor B2, mitochondrial
Overview

Dimethyladenosine transferase 2, mitochondrial is an enzyme that in humans is encoded by the TFB2M gene.
Synonyms

TFB2M; transcription factor B2, mitochondrial; dimethyladenosine transferase 2, mitochondrial; FLJ22661; FLJ23182; Hkp1; HCV NS5A transactivated protein 5; Mitochondrial 12S rRNA dimethylase 2; mitochondrial; Mitochondrial transcription factor B2; mtTFB2; N-adenosyl(rRNA) dimethyltransferase 2; S adenosylmethionine 6 N, N adenosyl(rRNA) dimethyltransferase 2; Dimethyladenosine transferase 2; h-mtTFB; h-mtTFB2; HCV NS5A-transactivated protein 5; Hepatitis C virus NS5A-transactivated protein 5; hTFB2M; Mitochondrial dimethyladenosine transferase 2; mtTFB; NS5ATP5; S-adenosylmethionine-6-N; TFB2M_HUMAN; Transcription Factor B2; OTTHUMP00000037974; S-adenos;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
MYC
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TFB2M-7205H	Recombinant Human Transcription Factor B2, Mitochondrial, His-tagged	E.coli	His	20-396aa	Inquiry
Human	TFB2M-3195H	Recombinant Human TFB2M, His-tagged	E.coli	His	c-221aa	$319 / 25ug
Human	TFB2M-1580H	Recombinant Human TFB2M protein	E.coli	N/A		Inquiry
Human	TFB2M-1135HCL	Recombinant Human TFB2M 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TFB2M-696H	Recombinant Human TFB2M Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Tfb2m-1131M	Recombinant Mouse Tfb2m Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Rat	TFB2M-6026R	Recombinant Rat TFB2M Protein	Mammalian Cell	His		Inquiry
Rat	TFB2M-5685R-B	Recombinant Rat TFB2M Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	TFB2M-5685R	Recombinant Rat TFB2M Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	TFB2M-6345Z	Recombinant Zebrafish TFB2M	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
TFB2M Related Articles

TFB2M involved in several pathways and played different roles in them. We selected most pathways TFB2M participated on our site, such as Energy Metabolism, Gene Expression, Mitochondrial Gene Expression, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFB2M were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Energy Metabolism	UCP2;GABPA;PPARGC1B;TFB2M;MYBBP1A;ESRRA;UCP3;MEF2B;TFB1M
Gene Expression	GATAD2B;ZNF577;NR2C1;ZNF155;DARS;RARG;PDCD7;ZNF680;CCNC
Mitochondrial Gene Expression	TFB2M;TFB1M;ESRRA;MTERFD1;POLRMT;PPARGC1B;PPRC1
Mitochondrial biogenesis	MTERF;POLG2;PPRC1;POLRMT;GABPB1;TFB2M;GABPA;TFB1M;PPARGC1B
Mitochondrial transcription initiation	TFB2M;POLRMT
Organelle biogenesis and maintenance	DYNLRB2;GFM1;MTRF1L;RABL5;TTC30A1;MRPL49;AURKAIP1;MRPL3;BBS9
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	CBX3A;SNAPC1B;POLR3GLA;CHD4;MBD3A;CRCP;MTERF;ZNF143A;MBD3
Transcription from mitochondrial promoters	TFB2M;POLRMT;MTERF

TFB2M has several biochemical functions, for example, poly(A) RNA binding, rRNA (adenine-N6,N6-)-dimethyltransferase activity, transcription cofactor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TFB2M itself. We selected most functions TFB2M had, and list some proteins which have the same functions with TFB2M. You can find most of the proteins on our site.

Function	Related Protein
poly(A) RNA binding	RPS12;RPS27A;ASS1;AKAP8;RPL26;POLR2A;SF3B4;NOL12;PSPC1
rRNA (adenine-N6,N6-)-dimethyltransferase activity	NDUFAF5;TFB1M;PRDM11;RNMTL1B;DIMT1L;FAM86;PRDM12;DIMT1;TFB2M
transcription cofactor activity	PHF21B;TAF13;HES6;ZNF710;BTG1;TMF1;ZFP710;LDB1B;IRF3

TFB2M has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFB2M here. Most of them are supplied by our site. Hope this information will be useful for your research of TFB2M.

TFAM; PHLDA3; ssrna_ug; C1qbp; Nek2; TUBG1; RAB4B; Ppp2ca; Gpkow; Cep131; Nup188; Tnpo1; Samm50; GAR1

Bao, L; Cai, XX; et al. Grape seed procyanidin B2 ameliorates mitochondrial dysfunction and inhibits apoptosis via the AMP-activated protein kinase-silent mating type information regulation 2 homologue 1-PPAR gamma co-activator-1 alpha axis in rat mesangial cells under high-dose glucosamine. BRITISH JOURNAL OF NUTRITION 113:35-44(2015).

Hayashi, G; Shen, Y; et al. Frataxin deficiency increases cyclooxygenase 2 and prostaglandins in cell and animal models of Friedreich's ataxia. HUMAN MOLECULAR GENETICS 23:6838-6847(2014).