tfec
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  • Official Full Name
  • transcription factor EC
  • Background
  • This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular processes including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
  • Synonyms
  • TFEC; transcription factor EC; bHLHe34; TCFEC; TFECL; Class E basic helix-loop-helix protein 34; hTFEC-L; TFE-C; TFEC protein; TFEC_HUMAN; Transcription factor EC-like; TFEC-L
Cat.#:TFEC-464HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TFEC Protein, His-tagged
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Cat.#:TFEC-16689MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TFEC Protein
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Cat.#:TFEC-6027RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat TFEC Protein
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Cat.#:TFEC-1376CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TFEC
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Cat.#:TFEC-3235ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TFEC
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Protein Function

TFEC has several biochemical functions, for example, DNA binding, protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TFEC itself. We selected most functions TFEC had, and list some proteins which have the same functions with TFEC. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein RFX5; FOXS1; GTF2I; TRIM33; ZNF350; ZNF777; FANCI; NR5A1B; LIN28B; ZFML
Function protein dimerization activity
Related Protein PEF1; HIF1AL; GARS; BHLHE41; MYCB; KIF9; POLR2J; MGAA; OLIG1; MITFB

TFEC Related Articles

Matsunaga, T; Ishida, T; et al. Analysis of gene expression during maturation of immature dendritic cells derived from peripheral blood monocytes. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 56:593-601(2002).
Zimmermann-Belsing, T; Rasmussen, AK; et al. The influence of alpha1-acid glycoprotein (orosomucoid) and its glycoforms on the function of human thyrocytes and CHO cells transfected with the human TSH receptor. MOLECULAR AND CELLULAR ENDOCRINOLOGY 188:241-251(2002).
FISHER, MB; HAYDEN, PJ; et al. FORMATION, CHARACTERIZATION, AND IMMUNOREACTIVITY OF LYSINE THIOAMIDE ADDUCTS FROM FLUORINATED NEPHROTOXIC CYSTEINE CONJUGATES INVITRO AND INVIVO. CHEMICAL RESEARCH IN TOXICOLOGY 6:223-230(1993).
HAYDEN, PJ; ICHIMURA, T; et al. DETECTION OF CYSTEINE CONJUGATE METABOLITE ADDUCT FORMATION WITH SPECIFIC MITOCHONDRIAL PROTEINS USING ANTIBODIES RAISED AGAINST HALOTHANE METABOLITE ADDUCTS. JOURNAL OF BIOLOGICAL CHEMISTRY 266:18415-18418(1991).