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TFG

Official Full Name

TRK-fused gene
Overview

There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.
Synonyms

TFG; TRK-fused gene; protein TFG; FLJ36137; TF6; OTTHUMP00000214045; OTTHUMP00000214046; OTTHUMP00000214047; OTTHUMP00000214048; TFG_HUMAN; TRK fused; TRK fused gene protein; TRK-fused gene protein; TRKT3; TRKT3 oncogene;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rhesus Macaque
Zebrafish

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	TFG-1125HCL	Recombinant Human TFG 293 Cell Lysate	HEK293	N/A	Inquiry
Human	TFG-1124HCL	Recombinant Human TFG 293 Cell Lysate	HEK293	N/A	Inquiry
Human	TFG-5794H	Recombinant Human TFG Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	Tfg-6381M	Recombinant Mouse Tfg Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Rhesus Macaque	TFG-4681R	Recombinant Rhesus monkey TFG Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	TFG-4497R	Recombinant Rhesus Macaque TFG Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rhesus Macaque	TFG-4497R-B	Recombinant Rhesus Macaque TFG Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	TFG-10374Z	Recombinant Zebrafish TFG	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein
TFG Related Articles

TFG involved in several pathways and played different roles in them. We selected most pathways TFG participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with TFG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Asparagine N-linked glycosylation	NAPB;CTAGE5;TRAPPC4;ST8SIA3;GORASP1;NSFB;PPP6R1;TRAPPC6BL;TRAPPC1
COPII (Coat Protein 2) Mediated Vesicle Transport	TRAPPC9;SEC23IP;SCFD1;PPP6C;GOLGA2;CTSC;NAPG;AREG;SEC22A
ER to Golgi Anterograde Transport	PPP6R3;SEC22A;CNIH3;NAPAA;MCFD2;GORASP1;TMED10;NSFA;TRAPPC4
Membrane Trafficking	ARCN1;SNAPIN;COPE;PICALMA;EXOC1;BLOC1S6;NECAP1;FTH1B;TMED10
Metabolism of proteins	MUC20;CBX8;DDX11;TRAPPC4;TMED2;GZMH;DNAJC24;PHC2;MAGT1
Pathways in cancer	FOS;RALB;TRAF3;DAPK1;PLCB4;MAPK10;NFKB1;FZD9;CKS2
Post-translational protein modification	ADAMTS15;SCFD1;WDR85;CNIH;RNF2;DHPS;SPON1;STT3A;CBX4
Thyroid cancer	TFG;TCF7L2;MAP2K1;CCDC6;TPM3;CDH1;TRP53;TP53;MAPK3

TFG has several biochemical functions, for example, protein binding, signal transducer activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TFG itself. We selected most functions TFG had, and list some proteins which have the same functions with TFG. You can find most of the proteins on our site.

Function	Related Protein
protein binding	PRMT8;PDGFB;SPHK1;NOG;HSPD1;KCNIP3;SMC1A;OLFM4;OLIG3
signal transducer activity	DRD1A;OLFR477;TAS2R201.1;MAPKAPK2A;STAT3;TAS2R200.1;OLFR491;RGS9;PLEKHG5

TFG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TFG here. Most of them are supplied by our site. Hope this information will be useful for your research of TFG.

BOLL; VPS37C; CEP55; SEC24A; CSTF2; HNRNPF; EWSR1

Guzman, E; Hope, J; et al. Bovine gamma delta T Cells Are a Major Regulatory T Cell Subset. JOURNAL OF IMMUNOLOGY 193:208-222(2014).

Masuda, C; Takeuchi, S; et al. Immunohistochemical Localization of an Isoform of TRK-Fused Gene-Like Protein in the Rat Retina. ACTA HISTOCHEMICA ET CYTOCHEMICA 47:75-83(2014).